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However, the specific effects and synergies of combining different CFs remain unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>The primary purpose of this study will be to determine if a CFs\u2010Enriched Standard Care (SC) approach is an effective treatment for MNP in terms of reducing pain and improving function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This will be an assessor\u2010blinded, 2\u2010group (1:1) randomised clinical trial (RCT) aiming to enrol 94 participants with neck pain persisting for more than 4\u00a0weeks. Both groups will undergo 4\u00a0weeks of SC twice weekly, following established clinical practice guidelines. In the intervention group, CFs will be enhanced, encompassing the physical, psychological, and social elements inherent in the clinical encounter, based on existing evidence. The primary outcomes will encompass changes in pain and disability after 4\u00a0weeks of treatment, with a follow\u2010up reassessment at week 12 post\u2010treatment. Secondary outcomes will include changes in Active Range of Motion, Global Rating of Change, and Satisfaction with treatment. The change between groups after treatment and at the 12\u2010week follow\u2010up will be reported for all outcomes, considering the difference from scores recorded at baseline.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We hypothesise that a 4\u2010week CFs\u2010Enriched SC approach will be superior to SC alone in terms of patient\u2010reported disability and pain, with measurements conducted using the Northwick Park Neck Pain Questionnaire and the Numeric Pain Rating Scale, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This RCT rigorously assesses the effect of purposeful manipulation of CFs during MNP treatment. By elucidating the role of these factors, our findings have the potential to significantly refine clinical practice in managing MNP, thereby enhancing patient care, and advancing the fields of physical therapy and rehabilitation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/msc.1894","type":"journal-article","created":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T08:14:05Z","timestamp":1715069645000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Contextual Factors\u2010Enriched Standard Care on mechanical neck pain (ContextualizAR trial): Protocol for a randomised controlled trial"],"prefix":"10.1002","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1880-3683","authenticated-orcid":false,"given":"Mauro Federico","family":"Andreu","sequence":"first","affiliation":[{"name":"Departamento de Ciencias de la Salud Universidad Nacional de La Matanza San Justo Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago","family":"Soli\u00f1o","sequence":"additional","affiliation":[{"name":"Hospital General de Agudos C. 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