{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:02:52Z","timestamp":1753869772911,"version":"3.41.2"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T00:00:00Z","timestamp":1738281600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We aimed to assess the effects of a patient therapeutic education (PTE) programme on the course of the disease and treatment management skills in rheumatoid arthritis (RA) patients treated with biologics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From January to December 2023, 52 RA patients participated in a face\u2010to\u2010face education session of 1\u00a0h, delivered to groups of four to six patients by 2 rheumatologists qualified in PTE. Disease activity, quality of life parameters and patient's skills using the BioSecure score were assessed before the education programme and 3\u00a0months later.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A statistically significant decrease in mean pain visual Analogue Scale (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.001), mean morning stiffness duration (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.002), mean number of night awakenings (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.01), mean tender joints count (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.001) and mean 28\u2010Disease\u2010activity\u2010score (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.001) were observed 3\u00a0months after the PTE. A statistically significant decrease in functional status (HAQ) and fatigue scores (FACIT\u2010F) was observed after PTE (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.03 and <jats:italic>p<\/jats:italic>\u00a0=\u00a00.001, respectively). The mean BioSecure score climbed from 47.9\u00a0\u00b1\u00a014.9 at baseline to 74.8\u00a0\u00b1\u00a012.9 after PTE (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.001). The variation of BioSecure score was significantly more important in patients with third\u2010level education, patients receiving subcutaneous biotherapy and those on TNF alpha inhibitors therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>PTE may be effective in improving clinical outcomes and safety skills in RA patients receiving biological treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/msc.70060","type":"journal-article","created":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T04:34:11Z","timestamp":1738384451000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy of Therapeutic Education for Patients With Rheumatoid Arthritis Treated With Biologics"],"prefix":"10.1002","volume":"23","author":[{"given":"Selma","family":"Bouden","sequence":"first","affiliation":[{"name":"Department of Rheumatology Charles Nicolle's Hospital  Tunis Tunisia"},{"name":"University of Tunis El Manar\u2013 Tunisia  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8126-5339","authenticated-orcid":false,"given":"Hiba Ben","family":"Ayed","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Charles Nicolle's Hospital  Tunis Tunisia"},{"name":"University of Tunis El Manar\u2013 Tunisia  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haifa","family":"Khemir","sequence":"additional","affiliation":[{"name":"University of Medicine\u00a0\u2013 Sousse  Sousse Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leila","family":"Rouached","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Charles Nicolle's Hospital  Tunis Tunisia"},{"name":"University of Tunis El Manar\u2013 Tunisia  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aicha Ben","family":"Tekaya","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Charles Nicolle's Hospital  Tunis Tunisia"},{"name":"University of Tunis El Manar\u2013 Tunisia  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ines","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Charles Nicolle's Hospital  Tunis Tunisia"},{"name":"University of Tunis El Manar\u2013 Tunisia  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raoudha","family":"Tekaya","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Charles Nicolle's Hospital  Tunis Tunisia"},{"name":"University of Tunis El Manar\u2013 Tunisia  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olfa","family":"Saidane","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Charles Nicolle's Hospital  Tunis Tunisia"},{"name":"University of Tunis El Manar\u2013 Tunisia  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leila","family":"Abdelmoula","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Charles Nicolle's Hospital  Tunis Tunisia"},{"name":"University of Tunis El Manar\u2013 Tunisia  Tunis Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,31]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.27860"},{"issue":"6","key":"e_1_2_11_3_1","first-page":"564","article-title":"\u00c9ducation Th\u00e9rapeutique Patient: Efficacit\u00e9 Au Cours de La Polyarthrite Rhumato\u00efde","volume":"101","author":"Abdelghani K. 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