{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T10:02:53Z","timestamp":1753869773083,"version":"3.41.2"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T00:00:00Z","timestamp":1738713600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of the study was to evaluate the ultrasonographic (United States) alterations of the median nerve, the performance of the Kamath screening questionnaire and the clinical examination (Tinel and Phanel test) in patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA) with previous or present inflammatory involvement of the radio\u2010ulno\u2010carpal joint.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>A cross\u2010sectional study was carried out. Patients with RA and PsA and clinical symptoms suggestive of CTS were consecutively recruited. The main clinical\u2010demographic characteristics were collected in all patients. The Kamath questionnaire was administered to all patients during the clinic visit. The US examination was used as a \u2018gold\u2010standard\u2019 for the diagnosis of CTS (transverse nerve area &gt;\u00a012\u00a0mm<jats:sup>2<\/jats:sup> and morpho\u2010structural alterations) and was used to assess the sensitivity and specificity of the Kamath questionnaire and the Tinel and Phanel clinical tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>44 patients, 34 patients with RA and 10 patients with PsA were evaluated. 7 (16%) patients had a median nerve cross\u2010sectional area &gt;\u00a012\u00a0mm<jats:sup>2<\/jats:sup>, associated with US abnormalities of the nerve. The Kamath questionnaire showed moderate sensitivity values (71.4%) but low specificity (56.7%) for ultrasonographic diagnosis of CTS with a negative predictive value of 91.3%. Clinical tests show low sensitivity but high specificity. No statistically significant correlations were found with the main clinical variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The screening questionnaire showed moderate sensitivity but low specificity compared to the ultrasound \u2018gold standard\u2019. Clinical tests may support the diagnosis of CTS in these conditions.<\/jats:p><\/jats:sec>","DOI":"10.1002\/msc.70063","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T01:59:12Z","timestamp":1738807152000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of Carpal Tunnel Syndrome in Patients With Wrist Involvement During the Course of Inflammatory Arthritis. A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3771-5205","authenticated-orcid":false,"given":"Fabio Massimo","family":"Perrotta","sequence":"first","affiliation":[{"name":"Dipartimento di Medicina e Scienze della Salute \u201cVincenzo Tiberio\u201d Universit\u00e0 degli Studi del Molise  Campobasso Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcella","family":"Antenucci","sequence":"additional","affiliation":[{"name":"Dipartimento di Medicina e Scienze della Salute \u201cVincenzo Tiberio\u201d Universit\u00e0 degli Studi del Molise  Campobasso Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello","family":"Zappia","sequence":"additional","affiliation":[{"name":"Dipartimento di Medicina e Scienze della Salute \u201cVincenzo Tiberio\u201d Universit\u00e0 degli Studi del Molise  Campobasso Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ennio","family":"Lubrano","sequence":"additional","affiliation":[{"name":"Dipartimento di Medicina e Scienze della Salute \u201cVincenzo Tiberio\u201d Universit\u00e0 degli Studi del Molise  Campobasso Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,5]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27584"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2024.12678"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(23)01525\u20108"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1539\/joh.16\u20100279\u2010OA"},{"issue":"4","key":"e_1_2_11_6_1","first-page":"164","article-title":"Determination of Cut\u2010Off Point of Cross\u2010Sectional Area of Median Nerve at the Wrist for Diagnosing Carpal Tunnel Syndrome","volume":"16","author":"Ghasemi M.","year":"2017","journal-title":"Iranian Journal of Neurology"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2006.055988"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0266\u20107681(03)00151\u20107"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100041\u20101741088"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296\u2010011\u20101957\u20100"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296\u2010020\u201004745\u20108"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016\u2010017\u20108637\u20100"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.190054"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/87564793231176009"},{"issue":"8","key":"e_1_2_11_15_1","first-page":"613","article-title":"The Best Cutoff Point for Median Nerve Cross Sectional Area at the Level of Carpal Tunnel Inlet","volume":"52","author":"Sarraf P.","year":"2014","journal-title":"Acta Medica Iranica"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.122259"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067\u2010020\u201005293\u2010z"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.21972"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.4078\/jrd.22.0028"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.084459"}],"container-title":["Musculoskeletal Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/msc.70063","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,13]],"date-time":"2025-04-13T03:01:37Z","timestamp":1744513297000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/msc.70063"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,5]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1002\/msc.70063"],"URL":"https:\/\/doi.org\/10.1002\/msc.70063","archive":["Portico"],"relation":{},"ISSN":["1478-2189","1557-0681"],"issn-type":[{"type":"print","value":"1478-2189"},{"type":"electronic","value":"1557-0681"}],"subject":[],"published":{"date-parts":[[2025,2,5]]},"assertion":[{"value":"2025-01-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70063"}}