{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T14:03:43Z","timestamp":1774533823502,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:00:00Z","timestamp":1743984000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,4,7]],"date-time":"2025-04-07T00:00:00Z","timestamp":1743984000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>This cross\u2010sectional study assesses the diagnostic and clinical utility of the 2\u2010item Generalised Anxiety Disorder Scale (GAD\u20102) for screening anxiety symptoms in individuals with persistent musculoskeletal pain attending physiotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In total, 450 patients (mean age\u00a0=\u00a053.3\u00a0\u00b1\u00a012.2\u00a0years; 109 male; mean illness duration\u00a0=\u00a00.5\u00a0\u00b1\u00a08.8\u00a0years) with persistent musculoskeletal pain were recruited in 84 private physiotherapy practices. Patients completed the Generalised Anxiety Disorder\u20107 (GAD\u20107) and GAD\u20102. Internal consistency was calculated for both measures. Area under the receiver operating characteristics curve (AUC) and Youden's\n                      <jats:italic>J<\/jats:italic>\n                      were calculated to determine the optimal GAD\u20102 cutoff score for identifying clinically significant anxiety symptoms, as defined by the previously validated GAD\u20107 cutoff score of\u00a0\u2265\u00a011 for persistent pain patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Internal consistency was good for the GAD\u20107 (Cronbach\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u00a0=\u00a00.89) and acceptable for the GAD\u20102 (\n                      <jats:italic>\u03b1<\/jats:italic>\n                      \u00a0=\u00a00.71). Both measures were moderately correlated (\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.39,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). GAD\u20102 had moderate overall accuracy for identifying clinically significant anxiety (AUC\u00a0=\u00a00.70; 95% confidence interval, 0.66\u20130.74). A GAD\u20102 cutoff score of\u00a0\u2265\u00a03 provided the most optimal balance of sensitivity (59%) and specificity (75%). Alternatively, a cutoff score of\u00a0\u2265\u00a02 provided a better sensitivity (70%) but worse specificity (56%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The GAD\u20102 is a clinically useful and psychometrically acceptable tool for screening anxiety symptoms in patients with persistent pain attending physiotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The GAD\u20102 has the potential to identify patients with persistent pain who are at risk of anxiety disorders and who may benefit from additional mental health support.<\/jats:p>\n                  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La Trobe University  Bendigo Australia"},{"name":"Department of Rural Health The University of Melbourne  Shepparton Australia"},{"name":"Allied Health Education and Research Unit Goulburn Valley Health  Shepparton Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wim","family":"Dankaerts","sequence":"additional","affiliation":[{"name":"KU Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dieter","family":"Van Assche","sequence":"additional","affiliation":[{"name":"KU Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica","family":"Lambrechts","sequence":"additional","affiliation":[{"name":"KU Leuven  Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brendon","family":"Stubbs","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry, Psychology, and Neuroscience King's College London  London UK"},{"name":"Department of Sport and Human 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