{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:34:12Z","timestamp":1792607652375,"version":"4.5.0"},"reference-count":78,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Gout is the most common form of inflammatory arthritis. It is predominantly managed with pharmacological interventions, and physical impairments in people with gout have seldom been studied. We aimed to identify gout\u2010related physical impairments that may be targeted by physical interventions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Five electronic databases (Medline, AMED, EMBASE, APA PsycInfo, CINAHL) were searched from inception to April 2024, together with reference lists of all included articles. We included all study designs, except for singular case reports, conducted in people with gout, where at least one objective physical impairment outcome was reported. All title, abstract and full\u2010text article eligibility screening was performed independently by two reviewers. Independent data extraction included design and setting, participant demographics, baseline characteristics, disease duration, physical impairment investigated, and method of assessment. Data synthesis was summarised descriptively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010four articles were included. Most studies were cross\u2010sectional designs in secondary care settings, 11 were performed in New Zealand. Participants' mean ages ranged from 41.3 (standard deviation (SD) not calculated) to 75.8 (SD 5.2) years. Participants were predominantly male. Gout duration ranged from 24\u00a0h to a mean of 28\u00a0years. Five broad categories of physical impairment were identified: lower extremity function, joint range of motion, strength, deformity, and Achilles tendon stiffness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Based on limited evidence, the most commonly observed physical impairments are related to lower extremity function and joint range of motion. Our review identifies the need to better understand and quantify gout\u2010related physical impairments before developing targeted physical interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/msc.70103","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T09:55:43Z","timestamp":1745315743000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Physical Impairments in People With Gout: A Scoping Review"],"prefix":"10.1002","volume":"23","author":[{"given":"Pranav","family":"Kumar","sequence":"first","affiliation":[{"name":"School of Medicine Keele University  Staffordshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenni","family":"Buckley","sequence":"additional","affiliation":[{"name":"School of Allied Health Professions and Pharmacy Keele University  Staffordshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Roddy","sequence":"additional","affiliation":[{"name":"Centre for Musculoskeletal Health Research School of Medicine Keele University  Staffordshire UK"},{"name":"Haywood Academic Rheumatology Centre Midlands Partnership University NHS Foundation Trust Haywood Hospital  Staffordshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4951-9925","authenticated-orcid":false,"given":"Martin J.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Centre for Musculoskeletal Health Research School of Medicine Keele University  Staffordshire UK"},{"name":"Haywood Academic Rheumatology Centre Midlands Partnership University NHS Foundation Trust Haywood Hospital  Staffordshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/RHU.0000000000000127"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891\u2010019\u20102537\u20109"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/1364557032000119616"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067\u2010020\u201004937\u20104"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0004\u20109514(14)60377\u20109"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/key096"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/eci.12862"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2022.2140842"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22648"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23607"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2018.04.020"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021\u20109290(87)90255\u20107"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/pzaa207"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035700"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(04)16000\u20105"},{"key":"e_1_2_11_17_1","first-page":"421","article-title":"Lesser Toe Abnormalities","volume":"52","author":"Coughlin M. 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