{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T13:16:07Z","timestamp":1784553367347,"version":"3.55.0"},"reference-count":35,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Systemic Sclerosis (SSc) is associated with substantial disability in affected patients. Although exercise interventions for SSc have been developed, most focus on isolated body segments rather than global disability. Thus, this study aims to assess the feasibility of a functional activity\u2010based exercise programme designed to address disability in individuals with SSc.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This feasibility study protocol is designed as a randomised controlled mixed\u2010methods trial. It will include individuals with SSc aged 18\u201365\u00a0years and with a score \u2265\u00a01 on the Scleroderma Health Assessment Questionnaire (SHAQ). Participants will be randomly allocated to either a control group, receiving an educational booklet on the disease, or an intervention group receiving the booklet plus a 10\u2010week supervised functional exercise protocol (twice weekly). Feasibility outcomes include recruitment and retention rates, adherence, safety, and adverse events. Preliminary clinical outcomes will address disability level, physical function, fatigue, resilience, symptoms of anxiety and depression, and perceived change. Quantitative data will be analysed using descriptive and inferential statistics, while qualitative data will undergo thematic content analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethical Approval<\/jats:title>\n                    <jats:p>The study was approved by the Institutional Ethics Committee (Approval Number: 6.992.710).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study is in its initial phase. The reference clinic has 219 registered patients, of whom 183 (83.6%) are preliminarily eligible. Recruitment and subsequent feasibility results are ongoing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This protocol proposes an innovative and low\u2010cost approach, whose results will support refinements for a more rigorous clinical trial, despite potential logistical and disease\u2010related limitations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/msc.70217","type":"journal-article","created":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:55:42Z","timestamp":1774918542000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Activity\u2010Based Functional Exercise for Disability in Systemic Sclerosis: Protocol for a Feasibility Randomised Controlled Trial"],"prefix":"10.1002","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5798-3376","authenticated-orcid":false,"given":"Gabriela","family":"da Silva Santos","sequence":"first","affiliation":[{"name":"Department of Physical Therapy Federal University of Pernambuco  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 Nunes","family":"Soares","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Federal University of Pernambuco  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geisielly Maria","family":"Porto Soares","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Federal University of Pernambuco  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tha\u00eds Ariadne","family":"Medeiros de Lima","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Federal University of Pernambuco  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Federal University of Pernambuco  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela Luzia","family":"Branco Pinto Duarte","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Federal University of Pernambuco  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e9lica","family":"da Silva Ten\u00f3rio","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Federal University of Pernambuco  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2345-3363","authenticated-orcid":false,"given":"Andrea Tavares","family":"Dantas","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Federal University of Pernambuco  Recife Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,30]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"An\u00e1lise de conte\u00fado","author":"Bardin L.","year":"2011"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20487"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0034\u201089101995000500004"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/jts.20271"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.014240"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1807\u201059322011000500004"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbr.2014.03.021"},{"key":"e_1_2_11_9_1","first-page":"31","article-title":"Adapta\u00e7\u00e3o Cultural e Contributo para a Valida\u00e7\u00e3o da Escala Patient Global Impression of Change","volume":"2","author":"Domingues L.","year":"2011","journal-title":"Ifisionline"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2016.06.069"},{"key":"e_1_2_11_11_1","volume-title":"ECDEU Assessment Manual for Psychopharmacology (Rev.)","author":"Guy W.","year":"1979"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kex182"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/pst.185"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kex193"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1989.00520460115022"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0363\u20105023(84)80146\u2010X"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40477\u2010023\u201000839\u20108"},{"issue":"3","key":"e_1_2_11_18_1","first-page":"69","article-title":"Adapta\u00e7\u00e3o transcultural da escala de gravidade de fadiga para a l\u00edngua portuguesa","volume":"27","author":"Mendes M. 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