{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:44:41Z","timestamp":1791873881000,"version":"4.3.4"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2026,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Plantar fasciitis is a common cause of chronic heel pain, and ultrasound\u2010guided biological injection therapies are increasingly used in patients refractory to conservative management. However, direct comparative data between platelet\u2010rich plasma (PRP) and ozone injections remain limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the short\u2010term clinical and functional outcomes of ultrasound\u2010guided PRP and ozone injections in patients with chronic plantar fasciitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients over 18\u00a0years of age diagnosed with plantar fasciitis via physical examination and radiological assessment, experiencing plantar fascia pain for more than 6\u00a0months, and unresponsive to conservative treatments were included. Visual Analog Scale scores and Foot Function Index scores, assessed at baseline and at 3\u2010month follow\u2010ups in the pain clinic, were retrospectively analysed and compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 43 injections were evaluated, distributed as 21 in the ozone group and 22 in the PRP group. Both groups demonstrated significant improvements in VAS and FFI scores at 3\u00a0months compared to baseline (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). When between\u2010group differences were analysed, the magnitude of improvement in the FFI\u2010Activity subscale and total FFI score was significantly greater in the PRP group than in the ozone group (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). No serious adverse events were observed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Both PRP and ozone injections are effective in reducing pain in patients with chronic plantar fasciitis; however, greater functional improvement was observed in the PRP group, particularly in activity\u2010related domains.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence<\/jats:title>\n                    <jats:p>Level III, retrospective comparative study.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/msc.70277","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T05:47:33Z","timestamp":1791870453000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of the Effectiveness of Ultrasound\u2010Guided Ozone and Platelet\u2010Rich Plasma Injections in Chronic Plantar Fasciitis"],"prefix":"10.1002","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5023-9373","authenticated-orcid":false,"given":"Burcu","family":"Ozalp","sequence":"first","affiliation":[{"name":"Department of Algology Faculty of Medicine Ege University  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8783-4603","authenticated-orcid":false,"given":"Derya","family":"Guner","sequence":"additional","affiliation":[{"name":"Department of Algology Izmir Health Sciences University Tepecik Training and Research Hospital  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/107110079801900207"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/1071100716666364"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1258\/shorts.2011.011148"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtumed.2025.01.002"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1123\/jsr.22.2.130"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/pm\/pny066"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2012.10.025"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.20150"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/10711007251346784"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010018\u201022402\u2010w"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009348.pub2"},{"issue":"12","key":"e_1_2_13_13_1","first-page":"224","article-title":"Effect of Ultrasound\u2010Guided Injection of Local Ozone or Platelet Rich Plasma Versus Corticosteroid in Plantar Fasciitis","volume":"1","author":"Elsawy A. 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