{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T09:45:54Z","timestamp":1791798354354,"version":"4.3.4"},"reference-count":51,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2024\/10092\u20104"],"award-info":[{"award-number":["2024\/10092\u20104"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2025\/06018\u20106"],"award-info":[{"award-number":["2025\/06018\u20106"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2015\/17777\u20103"],"award-info":[{"award-number":["2015\/17777\u20103"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2016\/11140\u20106"],"award-info":[{"award-number":["2016\/11140\u20106"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2026,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Musculoskeletal complaints are the leading cause of disability worldwide and are often associated with poor sleep quality. While evidence suggests that physical activity (PA) positively influences both pain management and sleep quality, it remains unclear whether PA influences the association between musculoskeletal complaints and sleep. This study aimed to investigate the association between musculoskeletal complaints and poor sleep quality, and whether PA modifies this association in adults from primary care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross\u2010sectional study analysed data from a Brazilian cohort. Musculoskeletal complaints were defined by self\u2010reported diagnosis of osteoarthritis or low back pain. Sleep quality was assessed using the Mini\u2010Sleep Questionnaire. PA was measured using the Baecke questionnaire. Binary logistic regression was used to test the association between musculoskeletal complaints and poor sleep quality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 557 patients were included (mean age 70.0\u00a0\u00b1\u00a08.4\u00a0years). Musculoskeletal complaints were associated with poor sleep quality even after adjusting for confounders (OR: 2.36 [95% CI: 1.56 to 3.57]). Stratified analyses showed that this association remained statistically significant among physically inactive participants (OR: 2.47 [95% CI: 1.51 to 4.05]), while the estimate among physically active participants was imprecise and included the null value (OR: 2.10 [95% CI: 0.95 to 4.62]). No statistically significant interaction between musculoskeletal complaints and PA was observed (\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value for interaction\u00a0=\u00a00.552).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Musculoskeletal complaints are associated with poor sleep quality. Although stratified analyses suggested different effect estimates according to PA, the formal interaction analysis did not support effect modification by PA. These findings should therefore be interpreted cautiously.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/msc.70280","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T08:56:56Z","timestamp":1791795416000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Physical Activity and the Association Between Musculoskeletal Complaints and Sleep Quality in Adults and Older Adults From Primary Care: A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-0860-5497","authenticated-orcid":false,"given":"Juliana Picchi","family":"Kappaum","sequence":"first","affiliation":[{"name":"Faculdade Israelita de Ci\u00eancias da Sa\u00fade Albert Einstein Einstein Hospital Israelita  Sao Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2775-860X","authenticated-orcid":false,"given":"Rafael Zambelli","family":"Pinto","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy Universidade Federal de Minas Gerais (UFMG)  Belo Horizonte Brazil"},{"name":"Physiotherapy Discipline University of Technology Sydney (UTS)  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2805-5746","authenticated-orcid":false,"given":"Ana Paula Coelho Figueira","family":"Freire","sequence":"additional","affiliation":[{"name":"Department of Health Sciences Central Washington University  Ellensburg Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4273-9375","authenticated-orcid":false,"given":"Jamile Sanches","family":"Codogno","sequence":"additional","affiliation":[{"name":"Department of Physical Education Sao Paulo State University (UNESP)  Presidente Prudente Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1314-6258","authenticated-orcid":false,"given":"Bruna Camilo","family":"Turi\u2010Lynch","sequence":"additional","affiliation":[{"name":"Department of Exercise Science and Human Performance Lander University  Greenwood South Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1576-8090","authenticated-orcid":false,"given":"R\u00f4mulo Ara\u00fajo","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Department of Physical Education Sao Paulo State University (UNESP)  Presidente Prudente Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6639-1532","authenticated-orcid":false,"given":"Henrique Luiz","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Department of Physical Education Sao Paulo State University (UNESP)  Bauru Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9245-287X","authenticated-orcid":false,"given":"\u00cdtalo Ribeiro","family":"Lemes","sequence":"additional","affiliation":[{"name":"Faculdade Israelita de Ci\u00eancias da Sa\u00fade Albert Einstein Einstein Hospital Israelita  Sao Paulo Brazil"},{"name":"Department of Physical Therapy Sao Paulo State University (UNESP)  Presidente Prudente Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(20)30925\u20109"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2017.08.001"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891\u2010018\u20102310\u20105"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586\u2010010\u20101661\u2010x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010024\u201003157\u20103"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/fmch\u20102024\u2010003056"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2010.02.069"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10143175"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/sms.13318"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889\u2010025\u201023549\u20108"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2024.03.040"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/33.5.585"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00038\u2010015\u20100657\u2010z"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102458\u201011\u2010275"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2019\/e722"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1590\/s0102\u2010311x2013000200019"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2022.105843"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2014.04.006"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325\u2010010\u20100392\u2010x"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569\u2010018\u20100064\u20102"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1590\/s0034\u201089102004000200022"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1517\u201086922003000300002"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2008.543"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(18)30480\u2010X"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e3181eef761"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare12050505"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12905\u2010025\u201003940\u20108"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.puhe.2018.11.007"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1123\/japa.2018\u20100094"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.14\u20101617"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci3010039"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.42089"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749\u20106632.1998.tb09569.x"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1590\/1980\u2010549720220032.2"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102474\u201014\u2010155"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2005.08.008"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2017.12.003"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0182013"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/sms.12581"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.26929"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000003279"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kead190"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.55563\/clinexprheumatol\/uol8so"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsae023"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2024.02.002"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2014.12.006"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1123\/jpah.2014\u20100368"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1080\/02640414.2019.1565109"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891\u2010018\u20102035\u20105"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12966\u2010020\u20100913\u20103"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10926\u2010023\u201010124\u20104"}],"container-title":["Musculoskeletal Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/msc.70280","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/msc.70280","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/msc.70280","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T08:56:58Z","timestamp":1791795418000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/msc.70280"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,12]]},"references-count":51,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["10.1002\/msc.70280"],"URL":"https:\/\/doi.org\/10.1002\/msc.70280","archive":["Portico"],"relation":{},"ISSN":["1478-2189","1557-0681"],"issn-type":[{"value":"1478-2189","type":"print"},{"value":"1557-0681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,12]]},"assertion":[{"value":"2026-05-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70280"}}