{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T10:11:49Z","timestamp":1761127909680},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2003,4,11]],"date-time":"2003-04-11T00:00:00Z","timestamp":1050019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2003,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Toxoplasma gondii<\/jats:italic> encysts in skeletal muscle. Although only rarely found at muscle biopsy, this parasite has previously been regarded as a possible cause of polymyositis. We report a case of biopsy\u2010proven toxoplasmic myositis in a non\u2013HIV\u2010infected patient that led to recognition of idiopathic CD4 lymphocytopenia (ICL), a rare condition typically associated with opportunistic infections. Interestingly, the CD25<jats:sup>+<\/jats:sup> subset that corresponds to the CD4<jats:sup>+<\/jats:sup> regulatory T cells controlling autoimmune processes was lacking. Steroid and antiprotozoal therapy led to recovery. Muscle Nerve 27: 761\u2013765, 2003<\/jats:p>","DOI":"10.1002\/mus.10376","type":"journal-article","created":{"date-parts":[[2003,5,20]],"date-time":"2003-05-20T11:35:04Z","timestamp":1053430504000},"page":"761-765","source":"Crossref","is-referenced-by-count":30,"title":["Toxoplasmic myositis as a presenting manifestation of idiopathic CD4 lymphocytopenia"],"prefix":"10.1002","volume":"27","author":[{"given":"Anne","family":"Plonquet","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillaume","family":"Bassez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois\u2010J\u00e9r\u00f4me","family":"Authier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Marc","family":"Dray","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Pierre","family":"Farcet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romain K.","family":"Gherardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,4,11]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880170721"},{"key":"e_1_2_5_3_2","first-page":"1556","article-title":"Skeletal muscle pathology in two siblings infected with T. gondii","volume":"27","author":"Calore EE","year":"2000","journal-title":"J Rheumatol"},{"key":"e_1_2_5_4_2","first-page":"541","article-title":"Unexplained CD4+ T lymphocyte depletion in persons without evident HIV infection","volume":"41","author":"Centers for Disease Control and Prevention","year":"1992","journal-title":"MMWR Morb Mortal Weekly Rep"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(97)00098-9"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.11.4.569"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410320409"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118464"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/clind\/24.4.676"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.16.9209"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.193.11.F41"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199302113280601"},{"key":"e_1_2_5_13_2","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1128\/cdli.3.5.611-613.1996","article-title":"Lymphocyte subset diversity in idiopathic CD4+ T lymphocytopenia","volume":"5","author":"Tassinari P","year":"1996","journal-title":"Clin Diagn Lab Immunol"},{"key":"e_1_2_5_14_2","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1182\/blood.V80.2.452.452","article-title":"Apoptotic cell death of primed CD45RO+ T lymphocytes in Epstein\u2010Barr virus\u2013induced infectious mononucleosis","volume":"80","author":"Uehara T","year":"1992","journal-title":"Blood"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.10376","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.10376","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T13:55:28Z","timestamp":1696859728000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.10376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,4,11]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2003,6]]}},"alternative-id":["10.1002\/mus.10376"],"URL":"https:\/\/doi.org\/10.1002\/mus.10376","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,4,11]]}}}