{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:27:28Z","timestamp":1792106848669,"version":"4.4.0"},"reference-count":153,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2003,10,28]],"date-time":"2003-10-28T00:00:00Z","timestamp":1067299200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2003,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The inflammatory myopathies include dermatomyositis (DM), polymyositis (PM), and sporadic inclusion\u2010body myositis (s\u2010IBM). In DM, the main immune effector response appears to be humoral and directed against the microvasculature, whereas in both PM and s\u2010IBM, cytotoxic CD8<jats:sup>+<\/jats:sup> T cells and macrophages invade and eventually destroy nonnecrotic muscle fibers expressing major histocompatibility complex class I. The need for more specific and safer therapies in inflammatory myopathies has prompted researchers to better decipher the molecular events associated with inflammation and muscle fiber loss in these diseases. The complex specific migration of leukocyte subsets to target tissues requires a coordinated series of events, namely activation of leukocytes, adhesion to the vascular endothelium, and migration. Cell adhesion molecules (CAM) and chemokines play a major role in this multistep process. In addition, cytokines by stimulating CAM expression and orchestrating T\u2010cell differentiation also influence the immune response. This review focuses on recent advances in defining the molecular events involved in leukocyte trafficking in inflammatory myopathies. Specific topics include a concise summary of clinical features, pathological findings and immunopathology observed in inflammatory myopathies, background information about cytokines, chemokines and cell adhesion molecules, and the expression of these molecules in inflammatory myopathies. Muscle Nerve 28: 659\u2013682, 2003<\/jats:p>","DOI":"10.1002\/mus.10462","type":"journal-article","created":{"date-parts":[[2003,11,20]],"date-time":"2003-11-20T18:19:45Z","timestamp":1069352385000},"page":"659-682","source":"Crossref","is-referenced-by-count":140,"title":["Cytokines, chemokines, and cell adhesion molecules in inflammatory myopathies"],"prefix":"10.1002","volume":"28","author":[{"given":"Dominique","family":"Figarella\u2010Branger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muriel","family":"Civatte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Bartoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Fran\u00e7ois","family":"Pellissier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,11,19]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1994.tb00854.x"},{"key":"e_1_2_7_3_2","first-page":"275","article-title":"The predominance of beta (CC) chemokine transcripts in idiopathic inflammatory muscle diseases","volume":"109","author":"Adams EM","year":"1997","journal-title":"Proc Assoc Am Physicians"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.162.6.3417"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.10.2030"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1006\/clim.1999.4823"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1994.tb00855.x"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)91384-4"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410190203"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/60.1.1"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1997.tb01195.x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.15.1.675"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.5.1033"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/1074-7613(95)90162-0"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.1994.tb06032.x"},{"key":"e_1_2_7_16_2","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1007\/s004010100394","article-title":"CCR2A and CCR2B, the two isoforms of the monocyte chemoattractant protein\u20101 receptor are up\u2010regulated and expressed by different cell subsets in idiopathic inflammatory myopathies","volume":"102","author":"Bartoli C","year":"2001","journal-title":"Acta Neuropathol (Berl)"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/120.6.929"},{"key":"e_1_2_7_18_2","doi-asserted-by":"crossref","first-page":"5943","DOI":"10.4049\/jimmunol.161.11.5943","article-title":"Human muscle cells express a functional costimulatory molecule distinct from B7.1 (CD80) and B7.2 (CD86) in vitro and in inflammatory lesions","volume":"161","author":"Behrens L","year":"1998","journal-title":"J Immunol"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.5.1863"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/320584a0"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/316552a0"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1636090"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0960-8966(96)00008-9"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3835(96)04569-7"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.164.2.746"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.7.2752"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.1.65"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.66.1.823"},{"key":"e_1_2_7_29_2","first-page":"467","article-title":"Leucocyte\/endothelial cell adhesion receptors in muscle biopsies from patients with idiopathic inflammatory myopathies (IM)","volume":"104","author":"Cid MC","year":"1996","journal-title":"Clin Exp Immunol"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199705000-00003"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/59.2.164"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)00074-1"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5447.2098"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199111213252107"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4892(01)00053-4"},{"key":"e_1_2_7_36_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.256.17.2381"},{"key":"e_1_2_7_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01335-3"},{"issue":"1","key":"e_1_2_7_38_2","first-page":"S4","article-title":"Beta chemokines and their receptors in inflammatory myopathies","volume":"199","author":"De Bleecker JL","year":"2002","journal-title":"J Neurol Sci"},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.12.1779"},{"key":"e_1_2_7_40_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199407000-00008"},{"key":"e_1_2_7_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(98)00126-6"},{"key":"e_1_2_7_42_2","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/12.9.1329"},{"key":"e_1_2_7_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(89)90228-1"},{"key":"e_1_2_7_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/1043-4666(90)90022-L"},{"key":"e_1_2_7_45_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/37.5.502"},{"key":"e_1_2_7_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0955-0674(96)80114-1"},{"key":"e_1_2_7_47_2","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(89)90128-7"},{"key":"e_1_2_7_48_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410270402"},{"key":"e_1_2_7_49_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410160207"},{"key":"e_1_2_7_50_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(86)80180-0"},{"key":"e_1_2_7_51_2","first-page":"1335","volume-title":"Myology","author":"Engel AG","year":"1994"},{"key":"e_1_2_7_52_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)62513-8"},{"key":"e_1_2_7_53_2","doi-asserted-by":"publisher","DOI":"10.1006\/cyto.1997.0308"},{"key":"e_1_2_7_54_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.42.091901.115838"},{"key":"e_1_2_7_55_2","first-page":"137","volume-title":"Inclusion body myositis and myopathies","author":"Figarella\u2010Branger D","year":"1998"},{"key":"e_1_2_7_56_2","first-page":"279","article-title":"Idiopathic inflammatory myopathies","volume":"21","author":"Figarella\u2010Branger D","year":"2001","journal-title":"Ann Pathol"},{"key":"e_1_2_7_57_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(90)90179-Q"},{"key":"e_1_2_7_58_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00296113"},{"key":"e_1_2_7_59_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81032-6"},{"key":"e_1_2_7_60_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410430123"},{"key":"e_1_2_7_61_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1997.00215.x"},{"key":"e_1_2_7_62_2","doi-asserted-by":"crossref","first-page":"4494","DOI":"10.4049\/jimmunol.150.10.4494","article-title":"Transforming growth factor\u2010beta inhibits E\u2010selectin expression on human endothelial cells","volume":"150","author":"Gamble JR","year":"1993","journal-title":"J Immunol"},{"key":"e_1_2_7_63_2","doi-asserted-by":"publisher","DOI":"10.1038\/19546"},{"key":"e_1_2_7_64_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118749"},{"key":"e_1_2_7_65_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410380504"},{"key":"e_1_2_7_66_2","first-page":"221","volume-title":"Structural and molecular basis of skeletal muscle disease","author":"Hohlfeld R","year":"2002"},{"key":"e_1_2_7_67_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410290509"},{"key":"e_1_2_7_68_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi971125s"},{"key":"e_1_2_7_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(92)90153-X"},{"key":"e_1_2_7_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90115-S"},{"key":"e_1_2_7_71_2","first-page":"81","article-title":"Signal transducer and activator of transcription 1 in human muscle: implications in inflammatory myopathies","volume":"151","author":"Illa I","year":"1997","journal-title":"Am J Pathol"},{"key":"e_1_2_7_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2776(08)60623-9"},{"key":"e_1_2_7_73_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830271223"},{"key":"e_1_2_7_74_2","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.38.632"},{"key":"e_1_2_7_75_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.162.7.4285"},{"key":"e_1_2_7_76_2","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.113.6.921"},{"key":"e_1_2_7_77_2","first-page":"527","article-title":"Pathology of the inflammatory myopathies","volume":"2","author":"Karpati G","year":"1993","journal-title":"Baillieres Clin Neurol"},{"key":"e_1_2_7_78_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410230111"},{"key":"e_1_2_7_79_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7973732"},{"key":"e_1_2_7_80_2","first-page":"953","article-title":"The membrane attack complex of complement induces interleukin\u20108 and monocyte chemoattractant protein\u20101 secretion from human umbilical vein endothelial cells","volume":"149","author":"Kilgore KS","year":"1996","journal-title":"Am J Pathol"},{"key":"e_1_2_7_81_2","first-page":"2019","article-title":"Sublytic concentrations of the membrane attack complex of complement induce endothelial interleukin\u20108 and monocyte chemoattractant protein\u20101 through nuclear factor\u2010kappa B activation","volume":"150","author":"Kilgore KS","year":"1997","journal-title":"Am J Pathol"},{"key":"e_1_2_7_82_2","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.4049\/jimmunol.155.3.1434","article-title":"Enhancement by the complement membrane attack complex of tumor necrosis factor\u2010alpha\u2010induced endothelial cell expression of E\u2010selectin and ICAM\u20101","volume":"155","author":"Kilgore KS","year":"1995","journal-title":"J Immunol"},{"key":"e_1_2_7_83_2","doi-asserted-by":"publisher","DOI":"10.1038\/nbt0797-641"},{"key":"e_1_2_7_84_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198602063140601"},{"key":"e_1_2_7_85_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1997.tb00065.x"},{"key":"e_1_2_7_86_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004010051165"},{"key":"e_1_2_7_87_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi990711d"},{"key":"e_1_2_7_88_2","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.4049\/jimmunol.145.7.2110","article-title":"IFN\u2010gamma regulates the expression of the adhesion molecule ELAM\u20101 and IL\u20106 production by human endothelial cells in vitro","volume":"145","author":"Leeuwenberg JF","year":"1990","journal-title":"J Immunol"},{"key":"e_1_2_7_89_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2990.1998.00092.x"},{"key":"e_1_2_7_90_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(99)00162-9"},{"key":"e_1_2_7_91_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004010000207"},{"key":"e_1_2_7_92_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004010051041"},{"key":"e_1_2_7_93_2","first-page":"12","article-title":"Expression of adhesion molecules in idiopathic inflammatory myopathies. Immuno\u2010histochemical study of 17 cases","volume":"19","author":"Liprandi A","year":"1999","journal-title":"Ann Pathol"},{"key":"e_1_2_7_94_2","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.116004"},{"key":"e_1_2_7_95_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.2.569"},{"key":"e_1_2_7_96_2","doi-asserted-by":"publisher","DOI":"10.1038\/34814"},{"key":"e_1_2_7_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5728(95)00122-0"},{"key":"e_1_2_7_98_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200002)43:2<336::AID-ANR13>3.0.CO;2-V"},{"key":"e_1_2_7_99_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400514"},{"key":"e_1_2_7_100_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199802123380706"},{"key":"e_1_2_7_101_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.164.11.5961"},{"key":"e_1_2_7_102_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.148.7.2142"},{"key":"e_1_2_7_103_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.167.5.2911"},{"key":"e_1_2_7_104_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(91)90033-P"},{"key":"e_1_2_7_105_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116533"},{"key":"e_1_2_7_106_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050087"},{"key":"e_1_2_7_107_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5699(97)81662-3"},{"key":"e_1_2_7_108_2","first-page":"73","article-title":"Properties of GMP\u2010140, an inducible granule membrane protein of platelets and endothelium","volume":"16","author":"McEver RP","year":"1990","journal-title":"Blood Cells"},{"key":"e_1_2_7_109_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1646376"},{"key":"e_1_2_7_110_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-6101(98)00024-0"},{"key":"e_1_2_7_111_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.160255197"},{"key":"e_1_2_7_112_2","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(96)80606-2"},{"key":"e_1_2_7_113_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(00)00161-9"},{"key":"e_1_2_7_114_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.8.1660"},{"key":"e_1_2_7_115_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200111000-00002"},{"key":"e_1_2_7_116_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.164.10.5459"},{"key":"e_1_2_7_117_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.16.9209"},{"key":"e_1_2_7_118_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.1998.00664.x"},{"key":"e_1_2_7_119_2","doi-asserted-by":"publisher","DOI":"10.1006\/clim.1999.4743"},{"key":"e_1_2_7_120_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90118-A"},{"key":"e_1_2_7_121_2","first-page":"940","article-title":"Increased expression of interleukin 1alpha and MHC class I in muscle tissue of patients with chronic, inactive polymyositis and dermatomyositis","volume":"27","author":"Nyberg P","year":"2000","journal-title":"J Rheumatol"},{"key":"e_1_2_7_122_2","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200111000-00003"},{"key":"e_1_2_7_123_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00738.2001"},{"key":"e_1_2_7_124_2","doi-asserted-by":"publisher","DOI":"10.1006\/clim.1999.4713"},{"key":"e_1_2_7_125_2","first-page":"934","article-title":"Dermatomyositis and polymyositis","volume":"158","author":"Pellissier JF","year":"2002","journal-title":"Rev Neurol (Paris)"},{"key":"e_1_2_7_126_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90451-4"},{"key":"e_1_2_7_127_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(00)00178-4"},{"key":"e_1_2_7_128_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199610313351807"},{"key":"e_1_2_7_129_2","doi-asserted-by":"publisher","DOI":"10.1053\/berh.1999.0076"},{"key":"e_1_2_7_130_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01543103"},{"key":"e_1_2_7_131_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5699(97)80019-9"},{"key":"e_1_2_7_132_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.277.5334.2005"},{"key":"e_1_2_7_133_2","doi-asserted-by":"publisher","DOI":"10.1007\/s100670070027"},{"key":"e_1_2_7_134_2","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.4049\/jimmunol.156.8.2851","article-title":"Human mucosal address in cell adhesion molecule\u20101 (MAdCAM\u20101) demonstrates structural and functional similarities to the alpha 4 beta 7\u2010integrin binding domains of murine MAdCAM\u20101, but extreme divergence of mucin\u2010like sequences","volume":"156","author":"Shyjan AM","year":"1996","journal-title":"J Immunol"},{"key":"e_1_2_7_135_2","doi-asserted-by":"crossref","first-page":"2891","DOI":"10.4049\/jimmunol.163.5.2891","article-title":"Signaling functions of L\u2010selectin in neutrophils: alterations in the cytoskeleton and colocalization with CD18","volume":"163","author":"Simon SI","year":"1999","journal-title":"J Immunol"},{"key":"e_1_2_7_136_2","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.119.5.1017"},{"key":"e_1_2_7_137_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90337-9"},{"key":"e_1_2_7_138_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.164.12.6593"},{"key":"e_1_2_7_139_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00812257"},{"key":"e_1_2_7_140_2","doi-asserted-by":"publisher","DOI":"10.1038\/380627a0"},{"key":"e_1_2_7_141_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5728(95)00045-4"},{"key":"e_1_2_7_142_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199603000-00009"},{"key":"e_1_2_7_143_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5728(00)00381-7"},{"key":"e_1_2_7_144_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1999.79.1.181"},{"key":"e_1_2_7_145_2","first-page":"1","volume-title":"The cytokine handbook","author":"Vilcek J","year":"1998"},{"key":"e_1_2_7_146_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90278-3"},{"key":"e_1_2_7_147_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00918135"},{"key":"e_1_2_7_148_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.180.5.1587"},{"key":"e_1_2_7_149_2","doi-asserted-by":"publisher","DOI":"10.1038\/380720a0"},{"key":"e_1_2_7_150_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.06.040188.002121"},{"key":"e_1_2_7_151_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0955-0674(00)00253-2"},{"key":"e_1_2_7_152_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65670-2"},{"key":"e_1_2_7_153_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.166.9.5755"},{"key":"e_1_2_7_154_2","first-page":"517","volume-title":"The cytokine handbook","author":"Zhang M","year":"1998"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.10462","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.10462","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T20:12:12Z","timestamp":1700251932000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.10462"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,11,19]]},"references-count":153,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2003,12]]}},"alternative-id":["10.1002\/mus.10462"],"URL":"https:\/\/doi.org\/10.1002\/mus.10462","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,11,19]]}}}