{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T08:34:29Z","timestamp":1774686869260,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2003,8,7]],"date-time":"2003-08-07T00:00:00Z","timestamp":1060214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In leprosy, sensory action potentials (SAPs) may be normal in spite of clinical sensory loss. This may result from the early involvement of small nerve fibers, which have potentials that are not detected in routine studies. To evaluate this possibility, we used a near\u2010nerve recording technique that records potentials from nerve fibers as small as 4\u20136 \u03bcm in diameter. We hypothesized that this technique might increase the sensitivity of nerve conduction studies in detecting leprosy neuropathy. We found the technique to be useful for recording conduction abnormalities in recently diagnosed patients, including those with preserved sensation, suggesting that axonal loss may be the underlying mechanism. Contrary to our hypothesis, however, recording the late SAP components did not improve the sensitivity of nerve conduction studies. We suggest that the late components having normal conduction velocities may be generated by either regenerating or remyelinating abnormal fibers, which have an electrophysiological behavior similar to that of normal 4\u20136\u2010\u03bcm\u2010diameter fibers. Muscle Nerve 28: 460\u2013463, 2003<\/jats:p>","DOI":"10.1002\/mus.10464","type":"journal-article","created":{"date-parts":[[2003,9,19]],"date-time":"2003-09-19T10:39:28Z","timestamp":1063967968000},"page":"460-463","source":"Crossref","is-referenced-by-count":14,"title":["Near\u2010nerve potential in lepromatous leprosy"],"prefix":"10.1002","volume":"28","author":[{"suffix":"Jr.","given":"Wilson","family":"Marques","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norma T.","family":"Foss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana P. M.","family":"Arruda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amilton A.","family":"Barreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,8,7]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"106","article-title":"Clinical, electrophysiological, quantitative, histological and ultrastructural studies of the index branch of the radial cutaneous nerve in leprosy. 1. Preliminary report","volume":"43","author":"Anthia NH","year":"1975","journal-title":"Int J Lepr"},{"key":"e_1_2_7_3_2","first-page":"981","volume-title":"Peripheral neuropathy","author":"Buchthal F","year":"1984"},{"key":"e_1_2_7_4_2","first-page":"47","article-title":"Ultrastructure of lepromatous nerves. 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A qualitative and quantitative study of sural nerve biopsies in 2 cases of lepromatous leprosy","volume":"59","author":"Gibbels E","year":"1988","journal-title":"Lepr Rev"},{"key":"e_1_2_7_7_2","first-page":"532","article-title":"Nerve damage in leprosy","volume":"57","author":"Job CK","year":"1989","journal-title":"Int J Lepr"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X1997001200008"},{"key":"e_1_2_7_9_2","first-page":"21","article-title":"Nerve conduction studies in leprosy","volume":"43","author":"Mcleod JG","year":"1975","journal-title":"Int J Lepr"},{"key":"e_1_2_7_10_2","first-page":"215","volume-title":"Handbook of clinical neurology: neuropathies","author":"Minauchi Y","year":"1987"},{"key":"e_1_2_7_11_2","first-page":"310","article-title":"Mononeuritis multiplex in lepromatous leprosy","volume":"198","author":"Rosenberg RN","year":"1969","journal-title":"Arch Neurol"},{"key":"e_1_2_7_12_2","first-page":"1354","volume-title":"Peripheral neuropathy","author":"Sabin TD","year":"1993"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880140608"},{"key":"e_1_2_7_14_2","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/BF00812152","article-title":"Asymptomatic nerve hypertrophy in lepromatous leprosy: a clinical, electrophysiological and morphological study","volume":"239","author":"Tzourio C","year":"1992","journal-title":"J Neurol"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.10464","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.10464","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T02:45:45Z","timestamp":1696905945000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.10464"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,8,7]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,10]]}},"alternative-id":["10.1002\/mus.10464"],"URL":"https:\/\/doi.org\/10.1002\/mus.10464","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,8,7]]}}}