{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:08:08Z","timestamp":1791320888081,"version":"4.3.1"},"reference-count":37,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2001,5,29]],"date-time":"2001-05-29T00:00:00Z","timestamp":991094400000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Subjects with chronic hemiplegia following stroke attempted to perform voluntary isometric, isokinetic, and free contractions of the extensor muscles of the metacarpophalangeal (MCP) joints. We recorded torque, metacarpophalangeal joint angle and velocity, and electromyographic (EMG) activity of the extrinsic extensors and flexors and the first dorsal interosseous (FDI). We found that voluntary MCP joint extension in hemiparetic subjects was greatly impaired in comparison with control subjects: only two of the 11 stroke subjects were able to generate even 0.21 N\u2010m of isometric extension torque, only two could produce positive finger extension with no load, and none could develop an isokinetic concentric extension. Deficits seemed to result from a combination of coactivation of the finger flexor and extensor muscles and decreased voluntary excitation of the extensors, as normalized flexor and FDI EMG activity were greater for stroke than for control subjects (<jats:italic>P<\/jats:italic> &lt; 0.001), but normalized extensor activity was reduced (<jats:italic>P<\/jats:italic> &lt; 0.001). \u00a9 2001 John Wiley &amp; Sons, Inc. Muscle Nerve 24: 673\u2013681, 2001<\/jats:p>","DOI":"10.1002\/mus.1054","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T21:24:42Z","timestamp":1030310682000},"page":"673-681","source":"Crossref","is-referenced-by-count":179,"title":["Impairment of voluntary control of finger motion following stroke: Role of inappropriate muscle coactivation"],"prefix":"10.1002","volume":"24","author":[{"given":"D.G.","family":"Kamper","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.Z.","family":"Rymer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2001,5,29]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(83)90074-X"},{"key":"e_1_2_6_3_2","first-page":"419","article-title":"Preliminary trial of carisoprodol in multiple sclerosis","volume":"192","author":"Ashworth B","year":"1964","journal-title":"Practitioner"},{"key":"e_1_2_6_4_2","first-page":"445","article-title":"Artificial feedforward as preparatory motor control in postictal hemiparesis","volume":"34","author":"Baykousheva\u2010Mateva V","year":"1994","journal-title":"Electromyogr Clin Neurophysiol"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.23.13486"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1987.sp016726"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(94)90278-X"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0924-980X(95)00262-J"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1994.tb09817.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/117.5.1161"},{"key":"e_1_2_6_11_2","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1017\/S0317167100023209","article-title":"EMG biofeedback in patients with motor disorders: aid for coordinating activity in antagonistic muscle groups","volume":"7","author":"Davis AE","year":"1980","journal-title":"Can J Neurol Sci"},{"key":"e_1_2_6_12_2","first-page":"247","article-title":"Impaired activation pattern in antagonistic elbow muscles of patients with spastic hemiparesis","volume":"33","author":"El\u2010Abd MAR","year":"1993","journal-title":"Electromyogr Clin Neurophysiol"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410360311"},{"key":"e_1_2_6_14_2","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1152\/jn.1984.51.1.32","article-title":"Cerebellar cortical activity during antagonist cocontraction and reciprocal inhibition of forearm muscles","volume":"51","author":"Fryinger RC","year":"1984","journal-title":"J Neurophysiol"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/72.9.624"},{"key":"e_1_2_6_16_2","first-page":"438","article-title":"Stretched position of spastic muscles aggravates their co\u2010contraction in hemiplegic patients","volume":"42","author":"Gracies JM","year":"1997","journal-title":"Ann Neurol"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.46.8.745"},{"key":"e_1_2_6_18_2","first-page":"348","article-title":"Cocontraction in the hemiparetic forearm: quantitative EMG evaluation","volume":"69","author":"Hammond MC","year":"1988","journal-title":"Arch Phys Med Rehabil"},{"key":"e_1_2_6_19_2","first-page":"259","article-title":"Functional electrical stimulation for the reduction of spasticity in the hemiplegic hand","volume":"29","author":"Hines AE","year":"1993","journal-title":"Biomed Sci Instrum"},{"key":"e_1_2_6_20_2","first-page":"393","article-title":"Separate cell systems in the motor cortex of the monkey for the control of joint movement and of joint stiffness","volume":"36","author":"Humphrey DR","year":"1982","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(200006)23:6<954::AID-MUS17>3.0.CO;2-0"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.30.12.1303"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0363-5023(92)90444-T"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.6.1210"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002210050830"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/89.2.359"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/112.3.681"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9993(94)90161-9"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-199612000-00010"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.3109\/03790798609166178"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410250106"},{"key":"e_1_2_6_32_2","first-page":"1149","article-title":"Coordination of multiple muscles in the elaboration of individual finger movements","author":"Rose CR","year":"1999","journal-title":"Soc Neurosci Abstr"},{"key":"e_1_2_6_33_2","doi-asserted-by":"publisher","DOI":"10.1177\/026921559701100102"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.44.8.690"},{"key":"e_1_2_6_35_2","first-page":"454","volume-title":"Occupational therapy for physical dysfunction","author":"Trombly CA","year":"1989"},{"key":"e_1_2_6_36_2","doi-asserted-by":"publisher","DOI":"10.5014\/ajot.37.3.195"},{"key":"e_1_2_6_37_2","doi-asserted-by":"publisher","DOI":"10.5014\/ajot.40.9.612"},{"key":"e_1_2_6_38_2","first-page":"591","article-title":"Evaluation of EMG parameters for analysis and quantification of hemiparesis","volume":"21","author":"Visser SL","year":"1981","journal-title":"Electromyogr Clin Neurophysiol"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.1054","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.1054","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T04:28:07Z","timestamp":1696912087000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.1054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":37,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["10.1002\/mus.1054"],"URL":"https:\/\/doi.org\/10.1002\/mus.1054","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,5]]}}}