{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:29:51Z","timestamp":1791217791530,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2001,10,18]],"date-time":"2001-10-18T00:00:00Z","timestamp":1003363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2001,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of the study was to determine whether abnormal median sensory nerve conduction among asymptomatic workers was predictive of future symptoms suggestive of carpal tunnel syndrome (CTS). This was a prospective study involving 77 workers who were identified as asymptomatic cases with electrodiagnostic findings of median mononeuropathy compared to an age\u2010 and sex\u2010matched control group. Follow\u2010up was completed an average of 70 months later, and subjects who reported pain, numbness, tingling, or burning in the distribution of the median nerve, based upon a hand diagram, were classified as having CTS symptoms. The follow\u2010up participation rate was 70%. Among subjects with abnormal median sensory latencies, 23% went on to develop symptoms consistent with CTS within the follow\u2010up period, compared with 6% in the control group (<jats:italic>P<\/jats:italic> = .010). Age and hand repetition were also risk factors for CTS, but the majority of asymptomatic workers with a median mononeuropathy do not become symptomatic over an extended time. \u00a9 2001 John Wiley &amp; Sons, Inc. 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