{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:20:23Z","timestamp":1771467623030,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,6,14]],"date-time":"2004-06-14T00:00:00Z","timestamp":1087171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2004,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Several studies have suggested that low\u2010level laser therapy (LLLT) is effective in patients with carpal tunnel syndrome (CTS). In a double\u2010blind randomized controlled trial of LLLT, 15 CTS patients, 34 to 67 years of age, were randomly assigned to either the control group (<jats:italic>n<\/jats:italic> = 8) or treatment group (<jats:italic>n<\/jats:italic> =7). Both groups were treated three times per week for 5 weeks. Those in the treatment group received 860 nm galium\/aluminum\/arsenide laser at a dosage of 6 J\/cm<jats:sup>2<\/jats:sup> over the carpal tunnel, whereas those in the control group were treated with sham laser. The primary outcome measure was the Levine Carpal Tunnel Syndrome Questionnaire, and the secondary outcome measures were electrophysiological data and the Purdue pegboard test. All patients completed the study without adverse effects. There was a significant symptomatic improvement in both the control (<jats:italic>P<\/jats:italic> = 0.034) and treatment (<jats:italic>P<\/jats:italic> =0.043) groups. However, there was no significant difference in any of the outcome measures between the two groups. Thus, LLLT is no more effective in the reduction of symptoms of CTS than is sham treatment. Muscle Nerve 30: 182\u2013187, 2004<\/jats:p>","DOI":"10.1002\/mus.20095","type":"journal-article","created":{"date-parts":[[2004,6,15]],"date-time":"2004-06-15T18:45:35Z","timestamp":1087325135000},"page":"182-187","source":"Crossref","is-referenced-by-count":80,"title":["Double\u2010blind randomized controlled trial of low\u2010level laser therapy in carpal tunnel syndrome"],"prefix":"10.1002","volume":"30","author":[{"given":"Jamie","family":"Irvine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su L.","family":"Chong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nasim","family":"Amirjani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. Ming","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,6,14]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(97)80155-4"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.3109\/17453679809002363"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900090103"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)62034-5"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900130602"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.1994.sp003755"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/acm.1999.5.5"},{"key":"e_1_2_7_9_2","first-page":"CD002049","article-title":"Low level laser therapy (classes I, II and III) in the treatment of rheumatoid arthritis","volume":"27","author":"Brosseau L","year":"2000","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_10_2","first-page":"1961","article-title":"Low level laser therapy for osteoarthritis and rheumatoid arthritis: a metaanalysis","volume":"27","author":"Brosseau L","year":"2000","journal-title":"J Rheumatol"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.5014\/ajot.54.5.555"},{"key":"e_1_2_7_12_2","volume-title":"Manual of nerve conduction velocity and somatosensory evoked potentials","author":"Delisa JA","year":"1987"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-002-0184-0"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.3109\/09638289509166638"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880160404"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0274(199903)35:3<232::AID-AJIM3>3.0.CO;2-G"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(01)00704-0"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/65.8.1184"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004200100285"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900090608"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199411000-00005"},{"key":"e_1_2_7_22_2","first-page":"19","article-title":"Open carpal tunnel release under local anaesthesia: a patient satisfaction survey","volume":"93","author":"Khan R","year":"2000","journal-title":"Ir Med J"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1089\/104454702760090173"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199311000-00002"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900140111"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.5014\/ajot.40.3.174"},{"key":"e_1_2_7_27_2","volume-title":"Aids to the examination of the peripheral nervous system","author":"Medical Research Council (Great Britain)","year":"1986"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1054\/jhsb.2000.0361"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/0020-1383(95)00048-E"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2002.33096"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1007\/s100720170030"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199809)21:9<1232::AID-MUS23>3.0.CO;2-S"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.2466\/pms.1988.66.2.503"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900090214"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-199001000-00003"},{"key":"e_1_2_7_36_2","doi-asserted-by":"publisher","DOI":"10.1089\/104454702753474995"},{"key":"e_1_2_7_37_2","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199606)9:3<197::AID-ANR1790090308>3.0.CO;2-W"},{"key":"e_1_2_7_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199708)20:8<1029::AID-MUS14>3.0.CO;2-Q"},{"key":"e_1_2_7_39_2","doi-asserted-by":"publisher","DOI":"10.1089\/104454701753342758"},{"key":"e_1_2_7_40_2","first-page":"208","article-title":"Successful management of female office workers with \u201crepetitive stress injury\u201d or \u201ccarpal tunnel syndrome\u201d by a new treatment modality\u2014application of low level laser","volume":"33","author":"Wong E","year":"1995","journal-title":"Int J Clin Pharmacol Ther"},{"key":"e_1_2_7_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(87)91430-2"},{"key":"e_1_2_7_42_2","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.1900090513"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.20095","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.20095","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T16:29:43Z","timestamp":1700238583000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.20095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6,14]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2004,8]]}},"alternative-id":["10.1002\/mus.20095"],"URL":"https:\/\/doi.org\/10.1002\/mus.20095","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,6,14]]}}}