{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T19:25:38Z","timestamp":1790277938786,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,7,7]],"date-time":"2005-07-07T00:00:00Z","timestamp":1120694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2005,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Various parameters of the repetitive nerve stimulation (RNS) test of the abductor digiti quinti muscle were analyzed statistically in 34 patients with Lambert\u2013Eaton myasthenic syndrome (LEMS). The sensitivity and specificity of the increments after exercise and after 50\u2010H\n                    <jats:sc>Z<\/jats:sc>\n                    stimulation for the diagnosis of LEMS were compared with reference values in 40 normal subjects and data from 538 tests in patients with myasthenia gravis (MG). When we used a 100% increment (the \u201cgold standard\u201d) as the normal limit for the postexercise facilitation (PEF) or the high\u2010rate stimulation (HRS) test, the diagnosis of LEMS was confirmed in 29 (85%) cases. When a 60% increment was used as the normal limit, the diagnosis of LEMS was made in 97% of cases. In MG, a 60% increment was observed in only 4 of 538 cases by HRS and in none by the exercise test. Thus, the use of a 60% increment showed a sensitivity of 97% for the diagnosis of LEMS and a specificity of 99% in excluding MG. A 60% increment in either the PEF or HRS test for the diagnosis of LEMS is a desirable alternative to the 100% increment previously considered to be the gold standard for this diagnosis. Muscle Nerve, 2005\n                  <\/jats:p>","DOI":"10.1002\/mus.20389","type":"journal-article","created":{"date-parts":[[2005,7,7]],"date-time":"2005-07-07T13:47:39Z","timestamp":1120744059000},"page":"515-520","source":"Crossref","is-referenced-by-count":147,"title":["Electrophysiological diagnostic criteria of Lambert\u2013Eaton myasthenic syndrome"],"prefix":"10.1002","volume":"32","author":[{"given":"Shin J.","family":"Oh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsumi","family":"Kurokawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwen C.","family":"Claussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"JR.","given":"Hewitt F.","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,7,7]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.1140"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0987-7053(05)80005-X"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.37.11.1214"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10477"},{"key":"e_1_2_6_6_2","first-page":"67","volume-title":"The remote effects of cancer on the nervous system","author":"Lambert E","year":"1965"},{"key":"e_1_2_6_7_2","first-page":"531","article-title":"Myasthenia gravis with electrophysiological features of Lambert\u2013Eaton myasthenic syndrome: usefulness of serum autoantibodies assay and neuromuscular biopsy","volume":"39","author":"Matsumoto R","year":"1999","journal-title":"Clin Neurol"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.54.5.452"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1974.00490390065006"},{"key":"e_1_2_6_10_2","first-page":"304","volume-title":"Electromyography. 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