{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T04:10:14Z","timestamp":1791346214401,"version":"4.3.1"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,5,31]],"date-time":"2007-05-31T00:00:00Z","timestamp":1180569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Long\u2010term occupational exposure to hand\u2013arm vibration can result in a permanent reduction in tactile sensitivity in exposed fingers and hands. Little is known about how vibration causes this reduction in sensitivity, and currently no testing procedures have been developed to monitor changes in sensory perception during ongoing exposures. We used a rat\u2010tail model of hand\u2013arm vibration syndrome (HAVS) to determine whether changes in sensory nerve function could be detected after acute exposure to vibration. Nerve function was assessed using the current perception threshold (CPT) method. We also determined whether changes in nerve function were associated with changes in gene transcription. Our results demonstrate that the CPT method can be used to assess sensory nerve function repeatedly in rats and can detect transient decreases in the sensitivity of A\u03b2 nerve fibers caused by acute exposure to vibration. This decrease in A\u03b2 fiber sensitivity was associated with a reduction in expression of nitric oxide synthase\u20101, and a modest increase in calcitonin gene\u2013related peptide transcript levels in tail nerves 24 h after vibration exposure. These transient changes in sensory perception and transcript levels induced by acute vibration exposure may be indicators of more prolonged changes in peripheral nerve physiology. Muscle Nerve, 2007<\/jats:p>","DOI":"10.1002\/mus.20804","type":"journal-article","created":{"date-parts":[[2007,5,31]],"date-time":"2007-05-31T17:16:39Z","timestamp":1180631799000},"page":"197-205","source":"Crossref","is-referenced-by-count":30,"title":["Acute vibration reduces A\u03b2 nerve fiber sensitivity and alters gene expression in the ventral tail nerves of rats"],"prefix":"10.1002","volume":"36","author":[{"given":"Kristine","family":"Krajnak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey","family":"Waugh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Wirth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael L.","family":"Kashon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,5,31]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"286","article-title":"Pentoxifylline, altitude and peripheral nerve function","volume":"4","author":"Appenzeller O","year":"1988","journal-title":"Ann Sports Med"},{"key":"e_1_2_6_3_2","first-page":"15","article-title":"Vascular responses to acute vibration in the fingers of normal subjects","volume":"3","author":"Bovenzi M","year":"1995","journal-title":"Cent Eur J Public Health"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004200050316"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/oem.57.6.422"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2052"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0007-1226(94)90136-8"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/oem.51.2.130"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-003-0486-x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.10058"},{"key":"e_1_2_6_11_2","first-page":"570","article-title":"Correspondence between neurological symptoms and outcome of quantitative sensory testing in the hand\u2013arm vibration syndrome","volume":"46","author":"Ekenvall L","year":"1989","journal-title":"Br J Indust Med"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2752(1998)18:7<397::AID-MICR2>3.0.CO;2-F"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1121\/1.392475"},{"key":"e_1_2_6_14_2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1177\/014107689408700703","article-title":"Cutaneous nerve fibre depletion in vibration white finger","volume":"87","author":"Goldsmith PC","year":"1994","journal-title":"J R Soc Med"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20478"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20578"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00235972"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1988.tb08295.x"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.3109\/02844318809097928"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh552"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.76.3.441"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(96)80166-3"},{"key":"e_1_2_6_23_2","first-page":"1","article-title":"Selective activation of primary afferent fibers evaluated by sine\u2010wave electrical stimulation","author":"Koga K","year":"2005","journal-title":"Mol Pain"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00761.2005"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20656"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1080\/00039890109604450"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2033"},{"key":"e_1_2_6_28_2","first-page":"360","article-title":"Temporary threshold shifts in fingertip vibratory sensation from hand\u2010transmitted vibration and repetitive shock","volume":"50","author":"Maeda S","year":"1993","journal-title":"Br J Ind Med"},{"key":"e_1_2_6_29_2","first-page":"185","article-title":"Temporary threshold shifts in fingertip vibratory sensation from hand\u2010transmitted vibration and repetitive shock","volume":"57","author":"Maeda S","year":"1994","journal-title":"Nagoya J Med Sci"},{"key":"e_1_2_6_30_2","first-page":"41","article-title":"An experimental study of the physiological effects of chain saw operation","volume":"44","author":"Miyakita T","year":"1987","journal-title":"Br J Indust Med"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2137"},{"key":"e_1_2_6_32_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02630738"},{"key":"e_1_2_6_33_2","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1152\/jn.1988.59.2.607","article-title":"Neural mechanisms in vibrotactile adaptation","volume":"59","author":"O'Mara S","year":"1988","journal-title":"J Neurophysiol"},{"key":"e_1_2_6_34_2","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2128"},{"key":"e_1_2_6_35_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-18-07236.2001"},{"key":"e_1_2_6_36_2","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2114"},{"key":"e_1_2_6_37_2","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.2046"},{"key":"e_1_2_6_38_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.2001.281.3.C849"},{"key":"e_1_2_6_39_2","doi-asserted-by":"publisher","DOI":"10.1159\/000147701"},{"key":"e_1_2_6_40_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-02-00363.2001"},{"key":"e_1_2_6_41_2","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.1953"},{"key":"e_1_2_6_42_2","doi-asserted-by":"publisher","DOI":"10.1121\/1.394047"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.20804","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.20804","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T01:47:15Z","timestamp":1697161635000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.20804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,31]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["10.1002\/mus.20804"],"URL":"https:\/\/doi.org\/10.1002\/mus.20804","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,31]]}}}