{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T22:29:10Z","timestamp":1785709750852,"version":"3.56.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2007,7,10]],"date-time":"2007-07-10T00:00:00Z","timestamp":1184025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2008,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A previously healthy 27\u2010year\u2010old woman developed a subacute myeloneuropathy after receiving nitrous oxide anesthesia for dental procedures. Neurologic evaluation revealed that she was vitamin B<jats:sub>12<\/jats:sub> deficient due to underlying pernicious anemia. Discontinuation of nitrous oxide and supplementation with vitamin B<jats:sub>12<\/jats:sub> resulted in dramatic clinical improvement, with near\u2010complete normalization of her neurologic examination. This case and published reports reviewed here emphasize that favorable outcomes are possible following prompt recognition and treatment of vitamin B<jats:sub>12<\/jats:sub> deficiency. Muscle Nerve, 2007<\/jats:p>","DOI":"10.1002\/mus.20840","type":"journal-article","created":{"date-parts":[[2007,7,10]],"date-time":"2007-07-10T21:21:45Z","timestamp":1184102505000},"page":"125-129","source":"Crossref","is-referenced-by-count":60,"title":["Reversible nitrous oxide\u2013induced myeloneuropathy with pernicious anemia: Case report and literature review"],"prefix":"10.1002","volume":"37","author":[{"given":"Mike A.","family":"Singer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Lazaridis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon P.","family":"Nations","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil I.","family":"Wolfe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,7,10]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2004.01.019"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.64.4.563"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1983.04050070046009"},{"key":"e_1_2_6_5_2","first-page":"1496","volume-title":"Neurology in clinical practice","author":"Bradley WG","year":"1999"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2000.107387"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1993.01420240099018"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.8.1435"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1994.tb03996.x"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199107000-00001"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1990.72.5.0732"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-1331.2002.00336.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.8.1608"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)92101-3"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)10090-9"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.57.3.380"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.6.1224"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.nu.12.070192.000423"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09611-3"},{"key":"e_1_2_6_20_2","first-page":"979","article-title":"Vitamin B12 deficiency","volume":"67","author":"Oh R","year":"2003","journal-title":"Am Fam Physician"},{"key":"e_1_2_6_21_2","first-page":"894","article-title":"Myelopathy caused by nitrous oxide toxicity","volume":"19","author":"Pema PJ","year":"1998","journal-title":"Am J Neuroradiol"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.60.3.354"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1986.03370120083027"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002340050812"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.7992049"},{"key":"e_1_2_6_26_2","first-page":"1224","article-title":"Subacute combined degeneration of the spinal cord: MR findings","volume":"14","author":"Timms SR","year":"1993","journal-title":"Am J Neuroradiol"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.20840","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.20840","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T15:29:16Z","timestamp":1697470156000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.20840"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7,10]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008,1]]}},"alternative-id":["10.1002\/mus.20840"],"URL":"https:\/\/doi.org\/10.1002\/mus.20840","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,7,10]]}}}