{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T05:31:22Z","timestamp":1792647082314,"version":"4.5.0"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2008,7,18]],"date-time":"2008-07-18T00:00:00Z","timestamp":1216339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2008,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We describe the process whereby a recently developed myasthenia gravis (MG)\u2010specific quality\u2010of\u2010life (QOL) instrument was reduced from 60 items to 15 items while maintaining potential usefulness in the clinic and in prospective treatment trials. In data from a recently completed prospective trial of mycophenolate mofetil (MMF) in MG, the MG\u2010QOL15 correlated as highly as the 60\u2010item MG\u2010QOL for physical and social domains of the 36\u2010item health survey of the Medical Outcomes Study Short Form (SF\u201036). Correlation coefficients for the MG\u2010QOL15 were similar to the 60\u2010item MG\u2010QOL for the Quantitative Myasthenia Gravis (QMG), MG\u2010specific Manual Muscle Testing (MG\u2010MMT), and the MG\u2010specific Activities of Daily Living (MG\u2010ADL) scores at week 0 and for change in scores from week 0 to week 12 in the MMF trial. Using the physician global impression at week 12 of the trial as the \u201cgold standard,\u201d the MG\u2010QOL15 demonstrated high sensitivity. Because the MG\u2010QOL15 instrument can be quickly and easily administered and interpreted, it is a potential QOL measure for treatment trials and the clinical evaluation of patients with MG. Muscle Nerve, 2008<\/jats:p>","DOI":"10.1002\/mus.21053","type":"journal-article","created":{"date-parts":[[2008,7,18]],"date-time":"2008-07-18T16:38:24Z","timestamp":1216399104000},"page":"957-963","source":"Crossref","is-referenced-by-count":179,"title":["Less is more, or almost as much: A 15\u2010item quality\u2010of\u2010life instrument for myasthenia gravis"],"prefix":"10.1002","volume":"38","author":[{"given":"Ted M.","family":"Burns","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Conaway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary R.","family":"Cutter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald B.","family":"Sanders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"The Muscle Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,7,28]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.322.7299.1417"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1998.tb11015.x"},{"key":"e_1_2_8_4_2","unstructured":"BurnsTM ConawayM SandersDB and theMuscle Study Group.Effect of quality\u2010of\u2010life on impairment of various regional domains in myasthenia gravis: MSG CellCept trial experience. The 11th International Conference on Myasthenia Gravis and Related Disorders May2007 Chicago IL."},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.1.16"},{"key":"e_1_2_8_6_2","article-title":"A disease\u2010specific measure of quality of life for myasthenia gravis","author":"Mullins LL","journal-title":"Muscle Nerve"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21053"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s100720200027"},{"key":"e_1_2_8_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.1034"},{"key":"e_1_2_8_10_2","doi-asserted-by":"publisher","DOI":"10.12968\/jowc.1996.5.3.139"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-006-0606-y"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1254.057"},{"key":"e_1_2_8_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000242887.79115.19"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21016"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199206000-00002"},{"key":"e_1_2_8_16_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.52.7.1487"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.21053","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.21053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T05:43:16Z","timestamp":1699940596000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.21053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,28]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["10.1002\/mus.21053"],"URL":"https:\/\/doi.org\/10.1002\/mus.21053","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,28]]}}}