{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T09:10:10Z","timestamp":1792919410856,"version":"4.5.0"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2009,7,17]],"date-time":"2009-07-17T00:00:00Z","timestamp":1247788800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NIH","award":["GM 67189"],"award-info":[{"award-number":["GM 67189"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Neuromuscular disorders frequently complicate sepsis and other critical illnesses in patients. Mice are the major species used as a model for sepsis. Nerve conduction studies (NCS), the primary tool for noninvasive assessment of nerve and muscle function, is challenging to perform in small animals. A reliable method for noninvasive, repeated NCS testing has not been reported in mice. We developed and validated a method for the repeated measurement of mouse sciatic nerve conduction in normal and septic mice. Our sedated and awake NCS system enabled minimally invasive long\u2010term repeated measurements. The mean compound muscle action potential (CMAP) amplitude and latency were 17.4 mV and 1.11 ms, respectively (\n                    <jats:italic>n<\/jats:italic>\n                    = 59). There was an excellent intertester reproducibility by linear regression in both normal (\n                    <jats:italic>r<\/jats:italic>\n                    = 0.95) and septic (\n                    <jats:italic>r<\/jats:italic>\n                    = 0.98) mice. We also showed significant, time\u2010dependent isoflurane\u2010induced CMAP suppression in all animals, which was further exacerbated in septic mice. This study provides a new tool for the assessment of peripheral nerve\/muscle function in mouse neuromuscular disease models that require repeated, long\u2010term, and minimally invasive monitoring. Muscle Nerve, 2009\n                  <\/jats:p>","DOI":"10.1002\/mus.21284","type":"journal-article","created":{"date-parts":[[2009,7,17]],"date-time":"2009-07-17T15:10:20Z","timestamp":1247843420000},"page":"610-616","source":"Crossref","is-referenced-by-count":30,"title":["Noninvasive model of sciatic nerve conduction in healthy and septic mice: Reliability and normative data"],"prefix":"10.1002","volume":"40","author":[{"given":"Marcin F.","family":"Osuchowski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Teener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Remick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,7,17]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2006.12.015"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410330115"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20304"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00024382-199908000-00005"},{"key":"e_1_2_7_6_2","first-page":"985","volume-title":"Principles of pharmacology: the pathophysiologic basis of drug therapy","author":"Golan DE","year":"2007"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.1092"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008506-199601000-00011"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000191414.94461.7e"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20786"},{"key":"e_1_2_7_11_2","first-page":"13","article-title":"Comparison of body surface temperature measurement and conventional methods for measuring temperature in the mouse","volume":"43","author":"Newsom DM","year":"2004","journal-title":"Contemp Top Lab Anim Sci"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.3.1967"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.1.623"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2005.04.006"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.2741\/1858"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0806542"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aeg224"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2005.02.006"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10974-006-9074-5"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-007-9023-9"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(80)90037-2"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-199604000-00012"},{"key":"e_1_2_7_23_2","first-page":"157","article-title":"General anesthetic effects on compound muscle action potentials elicited by single or dual spinal cord stimulation","volume":"8","author":"Yamada H","year":"1995","journal-title":"J Spinal Discord"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1999.tb08593.x"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.21284","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.21284","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.21284","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T22:08:02Z","timestamp":1697148482000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.21284"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,17]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["10.1002\/mus.21284"],"URL":"https:\/\/doi.org\/10.1002\/mus.21284","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,17]]}}}