{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:25:24Z","timestamp":1790645124997,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2010,5,25]],"date-time":"2010-05-25T00:00:00Z","timestamp":1274745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of this study was to describe the frequency of absent, unrecognized, or minimal myotonic discharges (MDs) in myotonic dystrophy type 2 (DM2). We performed a retrospective review of needle electromyography (EMG) data prior to genetic diagnosis in 49 DM2 patients at the Mayo Clinic. MDs were not reported on first or repeat EMG studies (<jats:italic>n<\/jats:italic> = 8) and not found in archived recordings of 4 patients (8%); archived EMG recordings (<jats:italic>n<\/jats:italic> = 4) confirmed the absence of MDs (<jats:italic>n<\/jats:italic> = 2), including 1 patient with normal insertional activity in all muscles, and misinterpretation of MDs as slow fibrillation potentials (<jats:italic>n<\/jats:italic> = 1) and complex repetitive discharge (CRD) activity (<jats:italic>n<\/jats:italic> = 1). Eight (16%) patients had minimal classic MDs with diffusely increased insertional activity, including waning\u2010only MDs in all patients in this group with archived EMG recordings (<jats:italic>n<\/jats:italic> = 5). Diffuse MDs were found in 33 (67%) patients. Absent or minimal MDs do not exclude DM2. Over\u2010reliance on diffuse MDs in patients who present with myopathy may lead to delay in genetic diagnosis of DM2. Muscle Nerve, 2010<\/jats:p>","DOI":"10.1002\/mus.21615","type":"journal-article","created":{"date-parts":[[2010,5,26]],"date-time":"2010-05-26T14:50:30Z","timestamp":1274885430000},"page":"758-762","source":"Crossref","is-referenced-by-count":45,"title":["Absent, unrecognized, and minimal myotonic discharges in myotonic dystrophy type 2"],"prefix":"10.1002","volume":"41","author":[{"given":"Nathan P.","family":"Young","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasper R.","family":"Daube","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric J.","family":"Sorenson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margherita","family":"Milone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,5,25]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000054481.84978.F9"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/570"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(98)00094-7"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1062125"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21150"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20289"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20923"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20638"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20722"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.10545"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410130228"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.1959.tb01668.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-282X2001000200006"},{"key":"e_1_2_5_15_2","first-page":"443","article-title":"Myotonic dystrophy sine myotonia: normal EMG in two obligate gene\u2010carriers of advanced age","volume":"27","author":"Streib EW","year":"1987","journal-title":"Electromyogr Clin Neurophysiol"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.1983.tb01857.x"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.21615","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.21615","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T00:25:02Z","timestamp":1696897502000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.21615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5,25]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["10.1002\/mus.21615"],"URL":"https:\/\/doi.org\/10.1002\/mus.21615","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,25]]}}}