{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T07:48:57Z","timestamp":1759564137674},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,1,12]],"date-time":"2012-01-12T00:00:00Z","timestamp":1326326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title><jats:italic>Introduction<\/jats:italic>:<\/jats:title><jats:p>Spinal and bulbar muscular atrophy (SBMA) and amyotrophic lateral sclerosis (ALS) are motor neuron diseases. Sensory impairment is sometimes observed, and electrophysiological involvement has been described in the sensory nerves of SBMA patients. We hypothesized that a sensory nerve conduction study (NCS) could be used to discriminate SBMA from ALS.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:italic>Methods<\/jats:italic>:<\/jats:title><jats:p>We compared the results from NCSs in a total of 120 SBMA cases confirmed by genetic analysis, 188 ALS cases, and 50 normal subjects.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:italic>Results<\/jats:italic>:<\/jats:title><jats:p>Sensory nerve action potential (SNAP) amplitudes of the SBMA group were significantly lower than in the ALS and control groups. In addition, receiver\u2010operating characteristic curve analysis for SNAP amplitude showed that a cut\u2010off value of 13.8 \u03bcV for median, 10.7 \u03bcV for ulnar, and 9.9 \u03bcV for sural nerve best discriminated SBMA from ALS.<\/jats:p><\/jats:sec><jats:sec><jats:title><jats:italic>Conclusions<\/jats:italic>:<\/jats:title><jats:p>The specific decrease of SNAP amplitude in SBMA provides another useful tool for the differential diagnosis of motor neuron diseases. Muscle Nerve, 2012<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.22291","type":"journal-article","created":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T19:26:18Z","timestamp":1314905178000},"page":"169-174","source":"Crossref","is-referenced-by-count":26,"title":["Discrimination of spinal and bulbar muscular atrophy from amyotrophic lateral sclerosis using sensory nerve action potentials"],"prefix":"10.1002","volume":"45","author":[{"given":"Tetsuo","family":"Hama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Hirayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Hara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiko","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Atsuta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruhiko","family":"Banno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keisuke","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahisa","family":"Katsuno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumiaki","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gen","family":"Sobue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,1,12]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.18.7.671"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/112.1.209"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/352077a0"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2006.01.021"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awl096"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.45.11.1012"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(95)00283-8"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00868997"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199703)20:3<323::AID-MUS9>3.0.CO;2-D"},{"key":"e_1_2_6_11_2","series-title":"Handbook of clinical neurology","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0072-9752(07)80016-9","author":"Leigh PN","year":"2007"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.49.2.568"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/146608200300079536"},{"key":"e_1_2_6_14_2","first-page":"91","volume-title":"Electrodiagnosis in diseases of nerve and muscle: principles and practice","author":"Kimura J","year":"2001"},{"key":"e_1_2_6_15_2","first-page":"130","volume-title":"Electrodiagnosis in diseases of nerve and muscle: principles and practice","author":"Kimura J","year":"2001"},{"key":"e_1_2_6_16_2","first-page":"439","volume-title":"Electrodiagnosis in diseases of nerve and muscle: principles and practice","author":"Kimura J","year":"2001"},{"key":"e_1_2_6_17_2","first-page":"307","volume-title":"Electrodiagnosis in diseases of nerve and muscle: principles and practice","author":"Kimura J","year":"2001"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/5.9.1253"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1086\/302578"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410320517"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.25.8.781"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00308818"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000286948.99150.16"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880180306"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440216"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh381"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm289"}],"container-title":["Muscle &amp; 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