{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T17:08:11Z","timestamp":1778692091678,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,7,16]],"date-time":"2012-07-16T00:00:00Z","timestamp":1342396800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction:<\/jats:title><jats:p>Our study aim was to produce a Japanese translation of the 15\u2010item Myasthenia Gravis Quality\u2010of\u2010Life Scale (MG\u2010QOL15), assess its reliability and validity, and examine clinical factors affecting self\u2010perceived QOL in MG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>We evaluated 327 consecutive patients with MG seen at six neurological centers. All patients completed the Japanese version of the MG\u2010QOL15 (MG\u2010QOL15\u2010J), the Beck Depression Inventory\u2014second edition (BDI\u2010II), and a generic health\u2010related QOL questionnaire, the SF\u201036. Disease severity was determined according to the Myasthenia Gravis Foundation of America (MGFA) quantitative MG score and the MG composite.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>The MG\u2010QOL15\u2010J exhibited adequate internal reliability, test\u2013retest repeatability, and concurrent validity with SF\u201036, disease severity, and known\u2010patient groups categorized by MGFA post\u2010intervention status. Multivariate analysis revealed severity, dose of oral corticosteroids, and BDI\u2010II as independent factors negatively affecting QOL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>The MG\u2010QOL15\u2010J is anticipated to be a valuable clinical measure of QOL in Japanese patients with MG. Muscle Nerve 46: 166\u2013173, 2012<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.23398","type":"journal-article","created":{"date-parts":[[2012,4,3]],"date-time":"2012-04-03T21:57:48Z","timestamp":1333490268000},"page":"166-173","source":"Crossref","is-referenced-by-count":95,"title":["The MG\u2010QOL15 Japanese version: Validation and associations with clinical factors"],"prefix":"10.1002","volume":"46","author":[{"given":"Masayuki","family":"Masuda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimiaki","family":"Utsugisawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeaki","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuriko","family":"Nagane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiaki","family":"Kabasawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroya","family":"Utsumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Fujihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichiro","family":"Uchiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norihiro","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,7,16]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1586\/14737175.9.3.351"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410150316"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000312373.67493.7f"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200721060-00004"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20950"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21053"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.1034"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21713"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.1.16"},{"key":"e_1_2_6_11_2","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s100720200027","article-title":"Myasthenia gravis outcome measure: development and validation of disease\u2010specific self\u2010administered questionnaire","volume":"23","author":"Padua L","year":"2002","journal-title":"Neurol Sci"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21016"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21053"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21609"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21883"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00095-X"},{"key":"e_1_2_6_17_2","volume-title":"Manual for Beck Depression Inventory\u2014II","author":"Beck AT","year":"1996"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(02)00106-3"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21185"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181dc1b1e"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.64.8.1121"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(93)90142-N"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200012150-00014"},{"key":"e_1_2_6_24_2","volume-title":"Manual of SF\u201036v2 Japanese version","author":"Fukuhara S","year":"2004"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2011-000313"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1159\/000319172"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1159\/000322497"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-8-129"}],"container-title":["Muscle &amp; 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