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The percentage of regenerating myofibers was not modified by the treatments. The drugs were effective in reducing COX\u20102 expression and inflammatory cytokines, but they did not affect utrophin levels. The effects of the treatments on contractile performance were analyzed. Isometric tension did not differ in treated and untreated muscle, but the resistance to fatigue was decreased by treatment with methylprednisolone and aspirin. <jats:italic>Conclusions:<\/jats:italic> NSAIDs have a beneficial effect on <jats:italic>mdx<\/jats:italic> muscle morphology, pointing to a crucial role of inflammation in the progression of DMD. Muscle Nerve, 2012<\/jats:p>","DOI":"10.1002\/mus.23432","type":"journal-article","created":{"date-parts":[[2012,4,30]],"date-time":"2012-04-30T06:19:55Z","timestamp":1335766795000},"page":"773-784","source":"Crossref","is-referenced-by-count":37,"title":["Inflammation in muscular dystrophy and the beneficial effects of non\u2010steroidal anti\u2010inflammatory drugs"],"prefix":"10.1002","volume":"46","author":[{"given":"Filippo","family":"Serra","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Quarta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Canato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luana","family":"Toniolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"De 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