{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:12:25Z","timestamp":1761513145356},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,10,5]],"date-time":"2012-10-05T00:00:00Z","timestamp":1349395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Introduction: We hypothesized that microvascular disturbances in muscle tissue play a role in the reduced exercise capacity in juvenile dermatomyositis (JDM). Methods: Children with JDM, children with juvenile idiopathic arthritis (clinical controls), and healthy children performed a maximal incremental cycloergometric test from which normalized concentration changes in oxygenated hemoglobin (\u0394[O<jats:sub>2<\/jats:sub>Hb]) and total hemoglobin (\u0394[tHb]) as well as the half\u2010recovery times of both signals were determined from the vastus medialis and vastus lateralis muscles using near\u2010infrared spectroscopy. Results: Children with JDM had lower \u0394[tHb] values in the vastus medialis at work rates of 25%, 50%, 75%, and 100% of maximal compared with healthy children; the increase in \u0394[tHb] with increasing intensity seen in healthy children was absent in children with JDM. Other outcome measures did not differ by group. Conclusions: The results suggest that children with JDM may experience difficulties in increasing muscle blood volume with more strenuous exercise. Muscle Nerve, 2013<\/jats:p>","DOI":"10.1002\/mus.23484","type":"journal-article","created":{"date-parts":[[2012,6,4]],"date-time":"2012-06-04T21:16:00Z","timestamp":1338844560000},"page":"108-115","source":"Crossref","is-referenced-by-count":12,"title":["Near\u2010infrared spectroscopy during exercise and recovery in children with juvenile dermatomyositis"],"prefix":"10.1002","volume":"47","author":[{"given":"G. 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