{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:31:51Z","timestamp":1782603111347,"version":"3.54.5"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,2,6]],"date-time":"2013-02-06T00:00:00Z","timestamp":1360108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>: Myasthenia gravis is an autoimmune disease marked by neuromuscular transmission failure at the neuromuscular junction. Castleman disease is a rare lymphoproliferative disease characterized by non\u2010cancerous angiofolicular hyperplasia of lymphatic tissue. <jats:italic>Methods and results<\/jats:italic>: We describe a young man with rapid, successive manifestations of myasthenia gravis, a solitary form of Castleman disease, pemphigus vulgaris, and anti\u2010phospholipid syndrome, which resulted in 2 ischemic cerebrovascular events that caused a severe central neurological deficit. <jats:italic>Discussion<\/jats:italic>: We were unable to find a similar case in the literature, but we hypothesize that the temporal concidence of these clinical entities may be related to a common immunological pathway, such as B\u2010cell activation. Therefore, we treated the patient with an immunosuppressant and anticoagulant treatment, as well as rituximab, a monoclonal antibody therapy against CD20+. <jats:italic>Muscle Nerve<\/jats:italic> 47:447\u2010451, 2013<\/jats:p>","DOI":"10.1002\/mus.23657","type":"journal-article","created":{"date-parts":[[2012,8,28]],"date-time":"2012-08-28T09:32:53Z","timestamp":1346146373000},"page":"447-451","source":"Crossref","is-referenced-by-count":22,"title":["Myasthenia gravis, castleman disease, pemphigus, and anti\u2010phospholipid syndrome"],"prefix":"10.1002","volume":"47","author":[{"given":"Michala","family":"Jakub\u00edkov\u00e1","sequence":"first","affiliation":[{"name":"Department of Neurology and Center of Clinical Neuroscience Charles University Prague First Faculty of Medicine and General University Hospital Prague Kate\u0159insk\u00e1 30, 128 01 Praha 2 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji\u0159\u00ed","family":"Pi\u0165ha","sequence":"additional","affiliation":[{"name":"Department of Neurology and Center of Clinical Neuroscience Charles University Prague First Faculty of Medicine and General University Hospital Prague Kate\u0159insk\u00e1 30, 128 01 Praha 2 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Latta","sequence":"additional","affiliation":[{"name":"Department of Neurology University Pardubice and Regional Hospital Pardubice Faculty of Health Studies Kyjevsk\u00e1 44, 53203 Pardubice Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edvard","family":"Ehler","sequence":"additional","affiliation":[{"name":"Department of Neurology University Pardubice and Regional Hospital Pardubice Faculty of Health Studies Kyjevsk\u00e1 44, 53203 Pardubice Czech 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