{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T15:19:58Z","timestamp":1766157598685},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2013,9]]},"abstract":"ABSTRACT<\/jats:title>Introduction<\/jats:title>Surface electromyography (SEMG) allows objective assessment and guides selection of appropriate treatment in focal hand dystonia (FHD).<\/jats:p><\/jats:sec>Methods<\/jats:title>Sixteen\u2010channel SEMG obtained during different phases of a writing task was used to study timing, activation patterns, and spread of muscle contractions in FHD compared with normal controls. Customized software was developed to acquire and analyze EMG signals.<\/jats:p><\/jats:sec>Results<\/jats:title>SEMG of FHD subjects (20) showed \u201cearly onset\u201d during motor imagery, rapid proximal muscle recruitment, agonist\u2010antagonist co\u2010contraction involving proximal muscle groups, \u201cdelayed offset\u201d after stopping writing, higher rectified mean amplitudes, and mirror activity in contralateral limb compared with controls (16). Muscle activation latencies were heterogenous in FHD.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Anticipation, delayed relaxation, and mirror EMG activation were noted in FHD. A clear pattern of muscle activation cannot be ascertained. Multi\u2010channel SEMG can aid in objective assessment of temporal\u2010spatial distribution of activity and can refine targeted therapies like chemodenervation and biofeedback. Muscle Nerve<\/jats:italic> 48<\/jats:bold>: 415\u2013422, 2013<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.23762","type":"journal-article","created":{"date-parts":[[2012,12,19]],"date-time":"2012-12-19T04:26:42Z","timestamp":1355891202000},"page":"415-422","source":"Crossref","is-referenced-by-count":8,"title":["Utility of multi\u2010channel surface electromyography in assessment of focal hand dystonia"],"prefix":"10.1002","volume":"48","author":[{"given":"Ajith","family":"Sivadasan","sequence":"first","affiliation":[{"name":"Department of Neurological Sciences Christian Medical College Vellore India 632004"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sanjay","sequence":"additional","affiliation":[{"name":"Department of Bioengineering Christian Medical College Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathew","family":"Alexander","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences Christian Medical College Vellore India 632004"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suresh R.","family":"Devasahayam","sequence":"additional","affiliation":[{"name":"Department of Bioengineering Christian Medical College Vellore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babu K.","family":"Srinivasa","sequence":"additional","affiliation":[{"name":"Department of Neurological Sciences Christian Medical College Vellore India 632004"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh527"},{"key":"e_1_2_7_3_1","first-page":"1","article-title":"Dystonia: abnormal movements result from loss of inhibition","volume":"94","author":"Hallet","year":"2004","journal-title":"Adv Neurol"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.38.7.1005"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.48.8.782"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/121.5.801"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10377"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.313.7072.1657"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20626"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.9.1813"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2004.043943"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20108"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2009.05.003"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20736"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2007.124594"}],"container-title":["Muscle & Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.23762","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.23762","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.23762","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T11:24:54Z","timestamp":1696332294000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.23762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,17]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["10.1002\/mus.23762"],"URL":"https:\/\/doi.org\/10.1002\/mus.23762","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,17]]}}}