{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T17:05:56Z","timestamp":1774717556142,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T00:00:00Z","timestamp":1399593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We examined the effects of gastrocnemius eccentric contractions (ECs) on the sciatic nerve in rats. <jats:italic>Methods<\/jats:italic>: Rats were divided randomly into the following 3 groups: control, 180EC (ECs with 180\u00b0\/s angular velocity), and 30EC (ECs with 30\u00b0\/s angular velocity). Twenty ECs were induced by electrical stimulation of the gastrocnemius. On days 3, 7, and 10 after the ECs, nerve conduction velocity (NCV) was measured, and sciatic nerve branches were harvested for analysis. <jats:italic>Results<\/jats:italic>: A significant decrease in NCV was observed between the control and day\u20107 180EC. Significant reduction in the levels of myelin sheath protein zero (p0) between day 7 and day 3 180EC and a significant increase of macrophage\u2010related protein and tyrosine kinase receptor C were observed between day 7 180EC and day 7 30EC. <jats:italic>Conclusions<\/jats:italic>: ECs with fast angular velocities induce functional and structural damage in innervating nerve. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>50<\/jats:bold>: 87\u201394, 2014<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.24120","type":"journal-article","created":{"date-parts":[[2013,11,12]],"date-time":"2013-11-12T05:42:55Z","timestamp":1384234975000},"page":"87-94","source":"Crossref","is-referenced-by-count":14,"title":["Eccentric contractions of gastrocnemius muscle\u2010induced nerve damage in rats"],"prefix":"10.1002","volume":"50","author":[{"given":"Kihyuk","family":"Lee","sequence":"first","affiliation":[{"name":"Graduate School of Health and Sport Science, Nippon Sport Science University Tokyo, 7\u20101\u20101, Fukasawa, Setagaya\u2010ku Tokyo 158\u20108508 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karina","family":"Kouzaki","sequence":"additional","affiliation":[{"name":"Graduate School of Health and Sport Science, Nippon Sport Science University Tokyo, 7\u20101\u20101, Fukasawa, Setagaya\u2010ku Tokyo 158\u20108508 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eisuke","family":"Ochi","sequence":"additional","affiliation":[{"name":"Laboratory of Health and Sports Sciences Center for Liberal Arts, Meiji Gakuin University Yokohama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Graduate School of Health and Sport Science, Nippon Sport Science University Tokyo, 7\u20101\u20101, Fukasawa, Setagaya\u2010ku Tokyo 158\u20108508 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