{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T15:00:11Z","timestamp":1788879611136,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T00:00:00Z","timestamp":1410825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007485","name":"Armed Forces Institute of Regenerative Medicine","doi-asserted-by":"crossref","award":["W81XWH-08-2-0034"],"award-info":[{"award-number":["W81XWH-08-2-0034"]}],"id":[{"id":"10.13039\/100007485","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Introduction<\/jats:italic>: Isometric muscle force measurement is a sensitive marker for motor function recovery in rat nerve repair models. Current methods of eliciting maximal isometric force with nerve stimulation cannot provide longitudinal data.<jats:italic>Methods<\/jats:italic>: We developed a novel method for measuring isometric muscle force with a device designed to allow minimally invasive nerve stimulation and measurement of plantar flexion force. This indirectly elicited muscle force was compared with muscle force elicited by direct muscle stimulation in 3 surgical models.<jats:italic>Results<\/jats:italic>: The force measured after sciatic nerve transection and repair followed a parabolic trend. There was a postinjury decrease in force that continued until postoperative day 42, after which the force increased with time, indicating muscle reinnervation.<jats:italic>Conclusions<\/jats:italic>: This approach can track longitudinal changes in force in the most common animal model for studies of clinically relevant problems in the peripheral nerve field.<jats:italic>Muscle Nerve<\/jats:italic><jats:bold>50<\/jats:bold>: 812\u2013821, 2014<\/jats:p>","DOI":"10.1002\/mus.24219","type":"journal-article","created":{"date-parts":[[2014,2,24]],"date-time":"2014-02-24T17:59:34Z","timestamp":1393264774000},"page":"812-821","source":"Crossref","is-referenced-by-count":3,"title":["Non\u2010invasive isometric force measurement of plantar flexors in rats"],"prefix":"10.1002","volume":"50","author":[{"given":"Aditya","family":"Chawla","sequence":"first","affiliation":[{"name":"Department of Neurologic Surgery Mayo Clinic 200 First Street SW Rochester Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Spinner","sequence":"additional","affiliation":[{"name":"Department of Neurologic Surgery Mayo Clinic 200 First Street SW Rochester Minnesota 55905"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Torres Lizardi","sequence":"additional","affiliation":[{"name":"University of Puerto Rico School of Medicine Puerto Rico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Yaszemski","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Mayo Clinic Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony J.","family":"Windebank","sequence":"additional","affiliation":[{"name":"Department of Neurology Mayo Clinic Rochester Minnesota 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