{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T01:17:27Z","timestamp":1778721447853,"version":"3.51.4"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,1,5]],"date-time":"2015-01-05T00:00:00Z","timestamp":1420416000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Introduction<\/jats:italic>: This diffusion tensor magnetic resonance imaging (DTI) study aimed to clarify the relationship of peripheral nerves and soft tissue tumors (STTs) in 3D to optimize subsequent treatment. <jats:italic>Methods<\/jats:italic>: Twenty\u2010six consecutive STT patients (histologically malignant, <jats:italic>n<\/jats:italic>\u2009=\u200910; intermediate, <jats:italic>n<\/jats:italic>\u2009=\u20093; and benign, <jats:italic>n<\/jats:italic>\u2009=\u200913) underwent 3\u2010Tesla MRI using an echoplanar DTI sequence. Deterministic tractography was performed. Fractional anisotropy (FA) values were measured within peritumoral and distant regions of interest. <jats:italic>Results<\/jats:italic>: Tractography depicted the 3D course of the sciatic (<jats:italic>n<\/jats:italic>\u2009=\u200912), femoral (<jats:italic>n<\/jats:italic>\u2009=\u20092), tibial (<jats:italic>n<\/jats:italic>\u2009=\u20097), fibular (<jats:italic>n<\/jats:italic>\u2009=\u20092), median (<jats:italic>n<\/jats:italic>\u2009=\u20091), musculocutaneous (<jats:italic>n<\/jats:italic>\u2009=\u20091), and ulnar (<jats:italic>n<\/jats:italic>\u2009=\u20091) nerves in a regular (<jats:italic>n<\/jats:italic>\u2009=\u20098 of 18, 44.4%) or thinned (<jats:italic>n<\/jats:italic>\u2009=\u20097 of 18, 38.9%) fashion. The lowest peritumoral FA values, abrupt thinning, and\/or complete discontinuity of trajectories were found in 2 cases with histologically proven tumoral nerve infiltration. <jats:italic>Conclusions<\/jats:italic>: DTI clarifies the 3D topography between major peripheral nerves and STTs and may be helpful in the assessment of peripheral nerve infiltration by malignant tumors. <jats:italic>Muscle Nerve<\/jats:italic> 51: 338\u2013345, 2015<\/jats:p>","DOI":"10.1002\/mus.24313","type":"journal-article","created":{"date-parts":[[2014,6,11]],"date-time":"2014-06-11T11:36:38Z","timestamp":1402486598000},"page":"338-345","source":"Crossref","is-referenced-by-count":28,"title":["Peripheral nerve tractography in soft tissue tumors: A preliminary 3\u2010tesla diffusion tensor magnetic resonance imaging study"],"prefix":"10.1002","volume":"51","author":[{"given":"Gregor","family":"Kasprian","sequence":"first","affiliation":[{"name":"Department of Biomedical Imaging and Image Guided Therapy Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Amann","sequence":"additional","affiliation":[{"name":"Department of Pathology Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joannis","family":"Panotopoulos","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manfred","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Dominkus","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siegfried","family":"Trattnig","sequence":"additional","affiliation":[{"name":"Department of Biomedical Imaging and Image Guided Therapy Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhard","family":"Windhager","sequence":"additional","affiliation":[{"name":"Department of Orthopedics Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Prayer","sequence":"additional","affiliation":[{"name":"Department of Biomedical Imaging and Image Guided Therapy Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris","family":"N\u00f6bauer\u2010Huhmann","sequence":"additional","affiliation":[{"name":"Department of Biomedical Imaging and Image Guided Therapy Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,1,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.161.2.3763909"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2382042192"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2301021640"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2403050916"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.10100343"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910320506"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2005.05.014"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.2423"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2005.12.014"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2004.01.073"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21553"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-008-0971-4"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-008-0577-6"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-007-0834-4"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.09.022"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0915-5"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.cco.0000166651.38417.c8"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1245\/aso.2002.9.1.41"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9098(200004)73:4<206::AID-JSO4>3.0.CO;2-5"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-77960-5_15"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.205.3.9393550"},{"key":"e_1_2_6_23_1","first-page":"427","volume-title":"Pathology and genetics of tumours of soft tissue and bone","author":"Fletcher CDM","year":"2002"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/02844319409015985"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.19.5.g99se101253"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01411304"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-49084-5_6"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1986.tb00159.x"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2004.07.016"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0745-5"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-007-0645-7"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.24313","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.24313","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.24313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T02:06:56Z","timestamp":1696558016000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.24313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,5]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1002\/mus.24313"],"URL":"https:\/\/doi.org\/10.1002\/mus.24313","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,5]]}}}