{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T06:41:16Z","timestamp":1696574476358},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,9,7]],"date-time":"2015-09-07T00:00:00Z","timestamp":1441584000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Introduction<\/jats:italic>: The aim of this study was to assess diagnoses and outcomes of infants with 2 or more cranial neuropathies identified using orofacial electromyography (EMG). <jats:italic>Methods<\/jats:italic>: This retrospective study involved 90 patients. Diagnoses took into account clinical, radiological, and genetic data. EMG examined the orbicularis oculi, genioglossus, and levator veli palatini muscles, and blink responses. To evaluate outcome, neurological disability, respiratory complications, and feeding difficulties were recorded. <jats:italic>Results<\/jats:italic>: The patients had malformation syndromes (59), encephalopathies (29), or no underlying disorders (2). Neurogenic EMG signs were detected in a mean of 4 muscles, reflecting a mean of 3 affected nerves. EMG identified a higher number of neuropathies than clinical examination alone (82 vs. 31, facial; 56 vs. 2, pharyngeal; 25 vs. 3, hypoglossal). Poor outcome and death were more frequent when EMG identified \u22654 affected nerves (<jats:italic>P<\/jats:italic>\u2009=\u20090.02). <jats:italic>Conclusion<\/jats:italic>: EMG highlights multiple cranial neuropathies that can be clinically silent in infants with malformation syndromes or encephalopathies. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>52<\/jats:bold>: 754\u2013758, 2015<\/jats:p>","DOI":"10.1002\/mus.24636","type":"journal-article","created":{"date-parts":[[2015,3,3]],"date-time":"2015-03-03T23:53:30Z","timestamp":1425426810000},"page":"754-758","source":"Crossref","is-referenced-by-count":4,"title":["Congenital multiple cranial neuropathies: Relevance of orofacial electromyography in infants"],"prefix":"10.1002","volume":"52","author":[{"given":"Francis","family":"Renault","sequence":"first","affiliation":[{"name":"Clinical Neurophysiology Unit, H\u00f4pital Armand\u2010Trousseau, Assistance Publique\u2010H\u00f4pitaux de Paris 28 avenue Arnold\u2010Netter, 75571 Paris 12 France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Flores\u2010Guevara","sequence":"additional","affiliation":[{"name":"Clinical Neurophysiology Unit, H\u00f4pital Armand\u2010Trousseau, Assistance Publique\u2010H\u00f4pitaux de Paris 28 avenue Arnold\u2010Netter, 75571 Paris 12 France"},{"name":"Facultad de Medicina, Universidad Nacional Mayor de San Marcos Lima Peru"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Jacques","family":"Baudon","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de M\u00e9decine Ren\u00e9\u2010Descartes, Universit\u00e9 Paris 5 Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie\u2010Paule","family":"Vazquez","sequence":"additional","affiliation":[{"name":"Facult\u00e9 de M\u00e9decine Ren\u00e9\u2010Descartes, Universit\u00e9 Paris 5 Paris France"},{"name":"Department of Maxillofacial Surgery H\u00f4pital Necker\u2010Enfants Malades, Assistance Publique\u2010H\u00f4pitaux de Paris Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,9,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2004.tb01026.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-3782(00)00073-6"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21991"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-008-0729-7"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000076484.91275.CD"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.125.1.33"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32179"},{"key":"e_1_2_6_9_1","first-page":"109\u2013113","article-title":"Anoxic\u2010ischemic encephalopathy in the human neonatal period","volume":"34","author":"Leech RW","year":"1977","journal-title":"The significance of brainstem involvement. 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