{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:31:49Z","timestamp":1791304309318,"version":"4.3.1"},"reference-count":66,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T00:00:00Z","timestamp":1448496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Introduction:<\/jats:italic> To assess whether a myasthenia gravis (MG) Lambert\u2010Eaton overlap syndrome (MLOS) exists. <jats:italic>Methods:<\/jats:italic> Case reports that met the universally accepted diagnostic criteria for MG and Lambert\u2010Eaton myasthenic syndrome (LEMS) were sought through a PubMed search. Fifty\u2010five possible cases of MLOS were identified. <jats:italic>Results:<\/jats:italic> Thirty\u2010nine cases met the diagnostic criteria for MG and LEMS. Analysis of clinical features showed that these patients have common MG and LEMS symptoms: oculo\u2010bulbar paresis and good response to anti\u2010cholinesterase for MG and limb weakness and decreased or absent reflexes for LEMS. All had the classical LEMS pattern in the repetitive nerve stimulation test: low compound muscle action potential amplitude and incremental response\u2009&gt;\u200960% with brief exercise or at high rate of stimulation. Eight patients had combined positive acetylcholine receptor antibody (AChR\u2010ab) or muscle\u2010specific kinase\u2010ab and voltage\u2010gated calcium channel\u2010 ab tests. <jats:italic>Conclusions:<\/jats:italic> A myasthenia gravis Lambert\u2010Eaton overlap syndrome (MLOS) does exist. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>53<\/jats:bold>: 20\u201326, 2016<\/jats:p>","DOI":"10.1002\/mus.24921","type":"journal-article","created":{"date-parts":[[2015,9,30]],"date-time":"2015-09-30T00:15:35Z","timestamp":1443572135000},"page":"20-26","source":"Crossref","is-referenced-by-count":31,"title":["Myasthenia gravis Lambert\u2010Eaton overlap syndrome"],"prefix":"10.1002","volume":"53","author":[{"given":"Shin J.","family":"Oh","sequence":"first","affiliation":[{"name":"Department of Neurology University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20389"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1974.00490390065006"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1972.00490160013002"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1966.tb45479.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410120406"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM193808182190703"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.21.1.47"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1974.00490370050006"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1987.tb51394.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.24.9.897"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.25.1.80"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.26.10.944"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00313148"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.26.9.882"},{"key":"e_1_2_6_16_1","first-page":"262","article-title":"Two cases of myasthenia gravis with neuromuscular transmission defects of Eaton\u2010Lambert syndrome type","volume":"28","author":"Arimura K","year":"1986","journal-title":"Clinical Rhinso Nouha (Japanese Journal)"},{"key":"e_1_2_6_17_1","first-page":"205","article-title":"Syndrome myasthenique avec bloc neuromusculaire mixte au cours d'un cancer bronchique","volume":"126","author":"Meignan M","year":"1975","journal-title":"Ann Med Interne"},{"key":"e_1_2_6_18_1","first-page":"398","article-title":"Combined Eaton\u2010Lambert syndrome and myasthenia gravis","volume":"28","author":"Fettel MR","year":"1978","journal-title":"Neurology"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.31.10.1345"},{"key":"e_1_2_6_20_1","first-page":"665","article-title":"A case of myasthenia gravis with malignant thymoma and features of Eaton\u2010Lambert syndrome","volume":"24","author":"Kusunoki S","year":"1984","journal-title":"Clin Neurol"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1986.00520090079023"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.51.6.880"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20735"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2012.8.4.305"},{"key":"e_1_2_6_25_1","first-page":"233","article-title":"Lambert Eaton mysthenic syndrome and myasthenia gravis","volume":"95","author":"Alvarez R","year":"1990","journal-title":"Med Clin (Barc)"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2012.8.3.235"},{"key":"e_1_2_6_27_1","first-page":"342","article-title":"Eaton\u2010Lambert syndrome caused by malignant thymoma in a patient with thymectomized myasthenia gravis","volume":"27","author":"Chiba S","year":"1987","journal-title":"Shinkei Naika (Japanese Journal)"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.1.218"},{"key":"e_1_2_6_29_1","first-page":"81","article-title":"Overlap myasthenic syndrome and thymoma","volume":"7","author":"Bertol V","year":"1992","journal-title":"Neurologia"},{"key":"e_1_2_6_30_1","first-page":"43","article-title":"Syndrome de Lambert\u2010Eaton et myasthenia. 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