{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T23:06:37Z","timestamp":1794006397154,"version":"4.8.0"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,12,23]],"date-time":"2015-12-23T00:00:00Z","timestamp":1450828800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NIH-NICHD","award":["5K12HD001097-17"],"award-info":[{"award-number":["5K12HD001097-17"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Introduction<\/jats:italic>: Although formal spirometry is the gold standard for monitoring respiratory function in patients with myasthenia gravis (MG), such testing is often delayed or unavailable. There is a need for a simple bedside test that can accurately measure respiratory function. <jats:italic>Methods<\/jats:italic>: We conducted a prospective, cross\u2010sectional, single\u2010blind study in adults with acetylcholine receptor antibody positive MG. Participants performed the single breath count test (SBCT) and underwent manual muscle strength testing, and a respiratory therapist performed spirometry blinded to SBCT and strength results. <jats:italic>Results<\/jats:italic> : Thirty\u2010one patients, aged 57\u2009\u00b1\u200919 years participated. SBCT showed significant correlations with forced vital capacity (FVC), negative inspiratory force, and neck flexor strength (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). FVC showed significant correlation with neck flexor strength (<jats:italic>P<\/jats:italic>\u2009=\u20090.02) but no correlation with shoulder abductor strength. <jats:italic>Conclusions<\/jats:italic>: These data suggest that the SBCT and neck flexor strength testing are valuable tools for bedside assessment of respiratory function in MG patients. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>53<\/jats:bold>: 134\u2013136, 2016<\/jats:p>","DOI":"10.1002\/mus.24929","type":"journal-article","created":{"date-parts":[[2015,10,6]],"date-time":"2015-10-06T08:44:48Z","timestamp":1444121088000},"page":"134-136","source":"Crossref","is-referenced-by-count":44,"title":["Correlation of single\u2010breath count test and neck flexor muscle strength with spirometry in myasthenia gravis"],"prefix":"10.1002","volume":"53","author":[{"given":"Bakri","family":"Elsheikh","sequence":"first","affiliation":[{"name":"Neurology, Johns Hopkins Aramco Healthcare Saudi Aramco P.O. Box 2614 Dhahran Saudi Arabia 31311"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. David","family":"Arnold","sequence":"additional","affiliation":[{"name":"Department of Neurology The Ohio State University Wexner Medical Center Columbus Ohio USA"},{"name":"Department of Physical Medicine and Rehabilitation The Ohio State University Wexner Medical Center Columbus Ohio USA"},{"name":"Department of Neuroscience The Ohio State University Wexner Medical Center Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahram","family":"Gharibshahi","sequence":"additional","affiliation":[{"name":"Neurology, Kaiser Permanente Neurology Panorama City California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerold","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Department of Neurology The Ohio State University Wexner Medical Center Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Freimer","sequence":"additional","affiliation":[{"name":"Department of Neurology The Ohio State University Wexner Medical Center Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John T.","family":"Kissel","sequence":"additional","affiliation":[{"name":"Department of Neurology The Ohio State University Wexner Medical Center Columbus Ohio USA"},{"name":"Department of Neuroscience The Ohio State University Wexner Medical Center Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70063-8"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-829593"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.48.5.1253"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20403"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-40757"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(94)70138-5"},{"key":"e_1_2_7_8_1","volume-title":"Muscles: testing and function","author":"Kendall FP","year":"1993"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2009.07.006"},{"key":"e_1_2_7_10_1","volume-title":"Disorders of neuromuscular transmission in neuromuscular disorders","author":"Amato AA","year":"2008"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-829595"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.24929","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.24929","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.24929","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T17:45:08Z","timestamp":1695491108000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.24929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,23]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["10.1002\/mus.24929"],"URL":"https:\/\/doi.org\/10.1002\/mus.24929","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,23]]}}}