{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:28:05Z","timestamp":1791300485536,"version":"4.1.0"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T00:00:00Z","timestamp":1465862400000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["HL078888"],"award-info":[{"award-number":["HL078888"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["HL085251"],"award-info":[{"award-number":["HL085251"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["T32-AR-048522"],"award-info":[{"award-number":["T32-AR-048522"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung and Blood Institute","doi-asserted-by":"crossref","award":["K08HL116640"],"award-info":[{"award-number":["K08HL116640"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Introduction<\/jats:italic>\n                    : Patients with self\u2010limited statin\u2010related myopathy improve spontaneously when statins are stopped. In contrast, patients with statin\u2010associated autoimmune myopathy have autoantibodies recognizing 3\u2010hydroxy\u20103\u2010methyl\u2010glutaryl\u2010coenzyme A reductase (HMGCR) and usually require immunosuppressive therapy to control their disease. On initial presentation, it can sometimes be difficult to distinguish between these 2 diseases, as both present with muscle pain, weakness, and elevated serum creatine kinase (CK) levels. The goal of this study was to determine whether patients with severe self\u2010limited statin\u2010related myopathy also make anti\u2010HMGCR autoantibodies.\n                    <jats:italic>Methods<\/jats:italic>\n                    : We screened 101 subjects with severe self\u2010limited cerivastatin\u2010related myopathy for anti\u2010HMGCR autoantibodies.\n                    <jats:italic>Results<\/jats:italic>\n                    : No patient with severe self\u2010limited cerivastatin\u2010related myopathy had anti\u2010HMGCR autoantibodies.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    : Anti\u2010HMGCR autoantibody testing can be used to help differentiate whether a patient has self\u2010limited myopathy due to cerivastatin or autoimmune statin\u2010associated myopathy; these findings may apply to other statins as well.\n                    <jats:italic>Muscle Nerve<\/jats:italic>\n                    <jats:bold>54<\/jats:bold>\n                    : 142\u2013144, 2016\n                  <\/jats:p>","DOI":"10.1002\/mus.25127","type":"journal-article","created":{"date-parts":[[2016,4,2]],"date-time":"2016-04-02T12:57:50Z","timestamp":1459601870000},"page":"142-144","source":"Crossref","is-referenced-by-count":26,"title":["Absence of anti\u2013HMG\u2010CoA reductase autoantibodies in severe self\u2010limited statin\u2010related myopathy"],"prefix":"10.1002","volume":"54","author":[{"given":"James S.","family":"Floyd","sequence":"first","affiliation":[{"name":"Department of Medicine University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Brody","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni","family":"Tiniakou","sequence":"additional","affiliation":[{"name":"Department of Medicine Johns Hopkins University School of Medicine Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce M.","family":"Psaty","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Washington Seattle Washington USA"},{"name":"Department of Epidemiology University of Washington Seattle Washington USA"},{"name":"Health Services University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Mammen","sequence":"additional","affiliation":[{"name":"Department of Medicine Johns Hopkins University School of Medicine Baltimore Maryland USA"},{"name":"National Institutes of Health Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,6,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.30156"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20662"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2011.295"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e328343dd7d"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.md.0000188565.48918.41"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21740"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2013.161"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.34673"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1506163"}],"container-title":["Muscle &amp; 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