{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T07:52:13Z","timestamp":1764402733153},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,11,28]],"date-time":"2016-11-28T00:00:00Z","timestamp":1480291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We report preliminary findings of nerve ultrasound in patients with cerebellar ataxia neuropathy vestibular areflexia syndrome (<jats:sc>C<\/jats:sc>ANVAS) who have sensory impairment due to dorsal root ganglionopathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The ultrasound cross\u2010sectional area (CSA) of median and ulnar nerves of 7 CANVAS patients was compared with 7 age\u2010 and gender\u2010matched controls and with the mean CSA of our reference population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The nerve CSA of CANVAS patients was significantly smaller than that of controls at all sites (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). All but 1 individual measurement of CSA at the mid\u2010forearm level in the CANVAS patients fell outside the normal control range and was &gt;2 standard deviations below the reference mean.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The small nerves in CANVAS probably reflect nerve thinning from axonal loss secondary to ganglion cell loss. Our data show a role for ultrasound in the diagnosis of CANVAS ganglionopathy. This may also be applicable to ganglionopathy from other causes. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>56<\/jats:bold>: 160\u2013162, 2017.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.25476","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T19:22:23Z","timestamp":1479324143000},"page":"160-162","source":"Crossref","is-referenced-by-count":25,"title":["Peripheral nerve ultrasound in cerebellar ataxia neuropathy vestibular areflexia syndrome (CANVAS)"],"prefix":"10.1002","volume":"56","author":[{"given":"Luciana","family":"Pelosi","sequence":"first","affiliation":[{"name":"Department of Neurology and Clinical Neurophysiology Bay of Plenty District Health Board Tauranga 3143 New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Leadbetter","sequence":"additional","affiliation":[{"name":"Capital and Coast District Health Board Wellington New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eoin","family":"Mulroy","sequence":"additional","affiliation":[{"name":"Auckland District Health Board Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew M.","family":"Chancellor","sequence":"additional","affiliation":[{"name":"Department of Neurology and Clinical Neurophysiology Bay of Plenty District Health Board Tauranga 3143 New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart","family":"Mossman","sequence":"additional","affiliation":[{"name":"Capital and Coast District Health Board Wellington New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Roxburgh","sequence":"additional","affiliation":[{"name":"Auckland District Health Board Auckland New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,11,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000352"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh030"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awu196"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.54.4.943"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3233\/VES-140536"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.178.6.1781553"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20673"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.21431"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2013.07.023"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24238"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.22035"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2014.01.033"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.25476","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.25476","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.25476","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T20:52:01Z","timestamp":1695761521000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.25476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,28]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1002\/mus.25476"],"URL":"https:\/\/doi.org\/10.1002\/mus.25476","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,28]]}}}