{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T13:58:07Z","timestamp":1761400687440},"reference-count":59,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,2,28]],"date-time":"2017-02-28T00:00:00Z","timestamp":1488240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>In humans, sensory nerve action potentials (SNAPs) can show 2 separate deflections, i.e., double peak potentials (DPp), which necessarily means that 1 peak is delayed with respect to the other. DPps may have various origins and be due to either physical or physiological properties.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We review the nature of commonly encountered DPps in clinical practice, provide the most likely interpretations for their physiological origin, and assess their reproducibility and clinical utility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We classified the DPps into 3 categories: (1) simultaneous anodal and cathodal stimulation. (2) simultaneous recording from 2 different nerves at the same site, and (3) SNAP desynchronization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Although the recording of DPps is not a standardized neurophysiological method, their study brings interesting cues about the physiology of nerve stimulation and paves the way for clinical application of such an observation. <jats:italic>Muscle Nerve<\/jats:italic> 55: 619\u2013625, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.25486","type":"journal-article","created":{"date-parts":[[2016,11,22]],"date-time":"2016-11-22T12:29:50Z","timestamp":1479817790000},"page":"619-625","source":"Crossref","is-referenced-by-count":3,"title":["Double peak sensory nerve action potentials to single stimuli in nerve conduction studies"],"prefix":"10.1002","volume":"55","author":[{"given":"Joao","family":"Leote","sequence":"first","affiliation":[{"name":"Neurosurgery Department, Hospital Garcia de Orta Almada 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