{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T18:29:27Z","timestamp":1712255367208},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,4,23]],"date-time":"2017-04-23T00:00:00Z","timestamp":1492905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007393","name":"Association Fran\u00e7aise contre les Myopathies","doi-asserted-by":"publisher","award":["19507"],"award-info":[{"award-number":["19507"]}],"id":[{"id":"10.13039\/100007393","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Patients with renal failure who are being treated with dialysis frequently develop neuromuscular manifestations. Renal failure\u2013associated calciphylaxis, also termed calcific uremic arteriolopathy (CUA), is a life\u2010threatening condition usually observed in patients with end\u2010stage renal disease on chronic dialysis or after renal transplantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We describe a hemodialyzed patient who presented with rapidly progressive unexplained systemic vasculopathy, muscle atrophy, and proximal weakness, that unexpectedly proved to be caused by calciphylaxis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Quadriceps muscle biopsy disclosed diffuse vascular calcific deposits on medium\u2010 and small\u2010sized vessels, characteristic of CUA. Other changes included ischemic myopathy, focal intracellular calcium accumulation within myofibers, and calcium deposits in endomysial capillaries associated with marked complement activation and C5b9 formation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There are only a few descriptions of muscle involvement in the context of CUA, a condition with a prognosis that depends on early diagnosis and treatment. This report underscores the usefulness of muscle biopsy in the diagnosis of systemic calciphylaxis. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>56<\/jats:bold>: 529\u2013533, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.25505","type":"journal-article","created":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T10:17:45Z","timestamp":1481278665000},"page":"529-533","source":"Crossref","is-referenced-by-count":5,"title":["Ischemic myopathy revealing systemic calciphylaxis"],"prefix":"10.1002","volume":"56","author":[{"given":"Jessie","family":"Aouizerate","sequence":"first","affiliation":[{"name":"Reference Center for Neuromuscular Diseases, H\u00f4pital Henri Mondor, Assistance Publique des H\u00f4pitaux de Paris (APHP); INSERM U955\u2010Team 10, Universit\u00e9 Paris Est\u2010Cr\u00e9teil 94 Avenue du Marechal de Lattre de Tassigny 94010 Creteil France"},{"name":"Transplantation and Nephrology Department H\u00f4pital Henri Mondor, APHP, Institut Francilien de recherche en N\u00e9phrologie et Transplantation, INSERM U955, Universit\u00e9 Paris Est\u2010Cr\u00e9teil Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurence","family":"Valleyrie\u2010Allanore","sequence":"additional","affiliation":[{"name":"Dermatology Department H\u00f4pital Henri Mondor, APHP Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Limal","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, H\u00f4pital Henri Mondor, APHP Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Samar","family":"Ayache","sequence":"additional","affiliation":[{"name":"Clinical Neurophysiology Department H\u00f4pital Henri Mondor, APHP, EA4391, Universit\u00e9 Paris Est\u2010Cr\u00e9teil Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romain K.","family":"Gherardi","sequence":"additional","affiliation":[{"name":"Reference Center for Neuromuscular Diseases, H\u00f4pital Henri Mondor, Assistance Publique des H\u00f4pitaux de Paris (APHP); INSERM U955\u2010Team 10, Universit\u00e9 Paris Est\u2010Cr\u00e9teil 94 Avenue du Marechal de Lattre de Tassigny 94010 Creteil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Audard","sequence":"additional","affiliation":[{"name":"Transplantation and Nephrology Department H\u00f4pital Henri Mondor, APHP, Institut Francilien de recherche en N\u00e9phrologie et Transplantation, INSERM U955, Universit\u00e9 Paris Est\u2010Cr\u00e9teil Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Jer\u00f4me Authier","sequence":"additional","affiliation":[{"name":"Reference Center for Neuromuscular Diseases, H\u00f4pital Henri Mondor, Assistance Publique des H\u00f4pitaux de Paris (APHP); INSERM U955\u2010Team 10, Universit\u00e9 Paris Est\u2010Cr\u00e9teil 94 Avenue du Marechal de Lattre de Tassigny 94010 Creteil France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,4,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-200301000-00009"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.6.1634"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2001.24533"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(200002)23:2<289::AID-MUS24>3.0.CO;2-H"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000332221"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.4161\/oxim.3.2.11354"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2011.01401.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2002.00375.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.5301\/JN.2011.6366"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.00803.x"},{"key":"e_1_2_5_12_1","first-page":"2015","article-title":"Calciphylaxis in the absence of renal failure and hyperparathyroidism in a nonagenarian","author":"Chan SQ","year":"2015","journal-title":"BMJ Case Rep"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00041552-200111000-00003"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.08.065"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(01)80129-3"},{"key":"e_1_2_5_16_1","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1177\/089686080802800313","article-title":"Calciphylaxis: the beginning of the end?","volume":"28","author":"Fine A","year":"2008","journal-title":"Peritoneal Dial Int"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181feb2d5"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.68.797.209"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00124743-199908000-00006"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-013-2580-6"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00530108"},{"key":"e_1_2_5_22_1","first-page":"e47","article-title":"et al","volume":"47","author":"Li YJ","year":"2006","journal-title":"Fulminant pulmonary calciphylaxis and metastatic calcification causing acute respiratory failure in a uremic patient. Am J Kidney Dis"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs466"},{"key":"e_1_2_5_24_1","first-page":"993","article-title":"Suspected systemic calcinosis and calciphylaxis in 5 horses","volume":"51","author":"Tan JY","year":"2010","journal-title":"La revue Veterinaire Canadienne"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-201822"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20386"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.124388"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.25505","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.25505","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.25505","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T20:58:39Z","timestamp":1696193919000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.25505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,23]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["10.1002\/mus.25505"],"URL":"https:\/\/doi.org\/10.1002\/mus.25505","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,23]]}}}