{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T07:49:15Z","timestamp":1786520955423,"version":"build-2736575974"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:00:00Z","timestamp":1490227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Head\u2010drop is often encountered in myasthenia gravis (MG) patients, but its frequency and clinical course have not been studied systematically.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a retrospective study of a cohort of MG patients seen over a period of 11 years in a tertiary medical center, we assessed the clinical characteristics of patients who had head\u2010drop.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 146 generalized MG patients, 15 had head\u2010drop during the course of their disease. Head\u2010drop patients had older age of onset than those who did not have head\u2010drop (mean age of onset 59.1 vs. 42.3 years) and were predominantly men. Head\u2010drop was present in 23% of patients\u2009&gt;\u200960 versus 6% of those\u2009&lt;\u200960 years, and it improved in 9 of 11 patients with treatment directed to generalized MG.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Head\u2010drop is a common, treatment\u2010responsive manifestation of late\u2010onset MG. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>56<\/jats:bold>: 441\u2013444, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.25526","type":"journal-article","created":{"date-parts":[[2016,12,21]],"date-time":"2016-12-21T08:53:19Z","timestamp":1482310399000},"page":"441-444","source":"Crossref","is-referenced-by-count":24,"title":["Head\u2010drop: A frequent feature of late\u2010onset myasthenia gravis"],"prefix":"10.1002","volume":"56","author":[{"given":"Marvin","family":"Sih","sequence":"first","affiliation":[{"name":"Department of Neurology University of Chicago Medical Center 5841 S. Maryland Avenue, MC 2030 Chicago Illinois 60637"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betty","family":"Soliven","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Chicago Medical Center 5841 S. Maryland Avenue, MC 2030 Chicago Illinois 60637"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Mathenia","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Chicago Medical Center 5841 S. Maryland Avenue, MC 2030 Chicago Illinois 60637"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Chicago Medical Center 5841 S. Maryland Avenue, MC 2030 Chicago Illinois 60637"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kourosh","family":"Rezania","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Chicago Medical Center 5841 S. 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