{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T22:40:00Z","timestamp":1782168000077,"version":"3.54.5"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:00:00Z","timestamp":1490227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Merkel cell carcinoma is a rare cutaneous, aggressive tumor. Although it shares many neuroendocrine features with small cell lung carcinoma, it has only occasionally been reported with paraneoplastic neurological syndromes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A healthy 67\u2010year\u2010old man developed acute ataxia, vertigo, and nausea. Subsequently he also developed dysarthria, diplopia, xerostomia, fatigability and progressive anorexia. He underwent a full diagnostic workup and was found to have a high titer of voltage\u2010gated calcium channel antibodies in serum and cerebrospinal fluid, neurophysiological findings compatible with Lambert\u2010Eaton myasthenia and neurological signs compatible with cerebellar degeneration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A positron emission tomography study revealed a hypermetabolic lesion in the axilla, subsequently biopsied and consistent with Merkel cell carcinoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In most previous reports, neurological symptoms preceded the Merkel cell carcinoma diagnosis, and the primary localization was in lymph nodes. This tumor should be considered in patients with paraneoplastic syndrome, and particularly Lambert\u2010Eaton myasthenia after exclusion of small cell lung carcinoma. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>56<\/jats:bold>: 998\u20131000, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.25530","type":"journal-article","created":{"date-parts":[[2016,12,24]],"date-time":"2016-12-24T14:28:59Z","timestamp":1482589739000},"page":"998-1000","source":"Crossref","is-referenced-by-count":12,"title":["Paraneoplastic cerebellar degeneration and lambert\u2010eaton myasthenia in a patient with merkel cell carcinoma and voltage\u2010gated calcium channel antibodies"],"prefix":"10.1002","volume":"56","author":[{"given":"Lucia","family":"Pavolucci","sequence":"first","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences (DiBiNeM) University of Bologna Via Altura 3, 40139 Bologna 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