{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T04:27:58Z","timestamp":1789014478660,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T00:00:00Z","timestamp":1490227200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Electrophysiological studies play an important role in the diagnosis of myasthenia gravis (MG). The objectives of this study was to explore the correlation of jitter and decrement with various clinical symptoms and signs and disease severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a retrospective chart review of 75\u2009MG patients who attended the neuromuscular clinic from April 2013 to May 2014. We compared clinical characteristics between patients with high jitter (&gt;100\u2009\u00b5s) and decrement (&gt;10%), and patients with lower values to explore the correlations and optimal thresholds of jitter and decrement for different clinical features.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>High jitter and decrement values were associated with more severe disease, manifested by more frequent symptomatic bulbar and limb muscle weakness, more frequent ocular and limb muscle weakness on examination, higher quantitative MG score, and generalized disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      The yield of the electrophysiological assessment in MG extends beyond disease diagnosis and correlates with disease severity and the presence of generalized disease.\n                      <jats:italic>Muscle Nerve<\/jats:italic>\n                      <jats:bold>56<\/jats:bold>\n                      : 445\u2013448, 2017\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mus.25539","type":"journal-article","created":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T11:23:54Z","timestamp":1482924234000},"page":"445-448","source":"Crossref","is-referenced-by-count":33,"title":["Electrophysiological testing is correlated with myasthenia gravis severity"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9020-2399","authenticated-orcid":false,"given":"Alon","family":"Abraham","sequence":"first","affiliation":[{"name":"Ellen and Martin Prosserman Centre for Neuromuscular Diseases Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto General Hospital 200 Elizabeth Street, Room 5 EB 309 Toronto Ontario Canada M5G 2C4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ari","family":"Breiner","sequence":"additional","affiliation":[{"name":"Ellen and Martin Prosserman Centre for Neuromuscular Diseases Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto General Hospital 200 Elizabeth Street, Room 5 EB 309 Toronto Ontario Canada M5G 2C4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Barnett","sequence":"additional","affiliation":[{"name":"Ellen and Martin Prosserman Centre for Neuromuscular Diseases Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto General Hospital 200 Elizabeth Street, Room 5 EB 309 Toronto Ontario Canada M5G 2C4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans D.","family":"Katzberg","sequence":"additional","affiliation":[{"name":"Ellen and Martin Prosserman Centre for Neuromuscular Diseases Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto General Hospital 200 Elizabeth Street, Room 5 EB 309 Toronto Ontario Canada M5G 2C4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leif E.","family":"Lovblom","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism Department of Medicine, Mount Sinai, Hospital and Lunenfeld Tanenbaum Research Institute, University of Toronto Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mylan Ngo","family":"RT","sequence":"additional","affiliation":[{"name":"Ellen and Martin Prosserman Centre for Neuromuscular Diseases Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto General Hospital 200 Elizabeth Street, Room 5 EB 309 Toronto Ontario Canada M5G 2C4"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Bril","sequence":"additional","affiliation":[{"name":"Ellen and Martin Prosserman Centre for Neuromuscular Diseases Division of Neurology, Department of Medicine, University Health Network, University of Toronto, Toronto General Hospital 200 Elizabeth Street, Room 5 EB 309 Toronto Ontario Canada M5G 2C4"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880140502"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.cnd.0000155026.66153.f0"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2011.02.026"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/CND.0b013e31824619d5"},{"key":"e_1_2_6_6_1","article-title":"Repetitive nerve stimulation cut\u2010off values for the diagnosis of Myasthenia Gravis","author":"Abraham A","year":"2016","journal-title":"Muscle Nerve Epub"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-200309000-00011"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25174"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(83)90095-3"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198703193161205"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1998.tb11015.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050585"},{"key":"e_1_2_6_13_1","first-page":"16","article-title":"Task Force of the Medical Scientific Advisory Board of the Myasthenia Gravis Foundation of America","volume":"55","author":"Myasthenia gravis: recommendations for clinical research standards","year":"2000","journal-title":"Neurology"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002971"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25214"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.1140"}],"container-title":["Muscle &amp; 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