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We tested the hypothesis that electrical impedance myography (EIM) can detect injury induced by maximal\u2010force lengthening contractions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We induced injury in the quadriceps of wild\u2010type (WT) and dystrophic (<jats:italic>mdx<\/jats:italic>) mice with eccentric contractions using an established model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>mdx<\/jats:italic> quadriceps had significantly greater losses in peak twitch and tetany compared with losses in WT quadriceps. Injured muscle showed a significant increase in EIM characteristic frequency in both WT (177\u2009\u00b1\u20097.7%) and <jats:italic>mdx<\/jats:italic> (167\u2009\u00b1\u20097.8%) quadriceps. EIM also revealed decreased extracellular resistance for both WT and <jats:italic>mdx<\/jats:italic> quadriceps after injury.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Our results show overall agreement between muscle function and EIM measurements of injured muscle, indicating that EIM is a viable tool to assess injury in dystrophic muscle. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>56<\/jats:bold>: E85\u2013E94, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.25559","type":"journal-article","created":{"date-parts":[[2017,1,5]],"date-time":"2017-01-05T23:12:46Z","timestamp":1483657966000},"source":"Crossref","is-referenced-by-count":23,"title":["Non\u2010invasive assessment of muscle injury in healthy and dystrophic animals with electrical impedance myography"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1594-9847","authenticated-orcid":false,"given":"Benjamin","family":"Sanchez","sequence":"first","affiliation":[{"name":"Department of Neurology Beth Israel Deaconess Medical Center, Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shama R.","family":"Iyer","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics University of Maryland School of Medicine AHB, Room 540, 100 Penn Street, Baltimore Maryland 21201 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Neurology Beth Israel Deaconess Medical Center, Harvard Medical School Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kush","family":"Kapur","sequence":"additional","affiliation":[{"name":"Department of Neurology 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