{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:48:39Z","timestamp":1792190919906,"version":"4.4.0"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,4,10]],"date-time":"2017-04-10T00:00:00Z","timestamp":1491782400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"National Health and Medical Research Council of Australia","award":["1037746"],"award-info":[{"award-number":["1037746"]}]},{"name":"International Federation of Clinical Neurophysiology Research Scholarship"},{"name":"Nakabayashi Trust for ALS research"},{"name":"2015 Australian Endeavour Executive Fellowship"},{"name":"University of Sydney Post-Doctoral Fellowship"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study seeks to elucidate the optimal scan time to detect fasciculations by using ultrasound in the diagnosis of amyotrophic lateral sclerosis (ALS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The intervals between fasciculations were recorded from tongue, abdominal, and limb muscles in ALS patients, incorporating assessment of the cumulative probability of 2 fasciculations occurring.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From prospective studies of 228 muscles from 19 ALS patients, fasciculations were detectable in 68% of patients. The longest interfasciculation interval recorded was 81.4 s in the hand muscle. The cumulative probability of 2 fasciculations occurring was calculated as \u22650.9 in all muscles during a period of 60 s.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>A definition of 2 or more fasciculations occurring during a scan time of 60 s reliably allowed detection of fasciculations in ALS. <jats:italic>Muscle Nerve<\/jats:italic>, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.25607","type":"journal-article","created":{"date-parts":[[2017,2,10]],"date-time":"2017-02-10T23:02:44Z","timestamp":1486767764000},"page":"1068-1071","source":"Crossref","is-referenced-by-count":38,"title":["Detection of fasciculations in amyotrophic lateral sclerosis: The optimal ultrasound scan time"],"prefix":"10.1002","volume":"56","author":[{"given":"Yu\u2010ichi","family":"Noto","sequence":"first","affiliation":[{"name":"Brain and Mind Centre Sydney Medical School, University of Sydney 94 Mallett Street, Camperdown, Sydney New South Wales 2040 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazumoto","family":"Shibuya","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre Sydney Medical School, University of Sydney 94 Mallett Street, Camperdown, Sydney New South Wales 2040 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nortina","family":"Shahrizaila","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre Sydney Medical School, University of Sydney 94 Mallett Street, Camperdown, Sydney New South Wales 2040 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Huynh","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre Sydney Medical School, University of Sydney 94 Mallett Street, Camperdown, Sydney New South Wales 2040 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 M.","family":"Matamala","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre Sydney Medical School, University of Sydney 94 Mallett Street, Camperdown, Sydney New South Wales 2040 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanuja","family":"Dharmadasa","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre Sydney Medical School, University of Sydney 94 Mallett Street, Camperdown, Sydney New South Wales 2040 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew C.","family":"Kiernan","sequence":"additional","affiliation":[{"name":"Brain and Mind Centre Sydney Medical School, University of Sydney 94 Mallett Street, Camperdown, Sydney New South Wales 2040 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,10]]},"reference":[{"issue":"8509","key":"e_1_2_6_2_1","first-page":"731","article-title":"Differential diagnosis of motoneurone disease from other neurological conditions","volume":"2","author":"Li TM","year":"1986","journal-title":"Lancet"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880130108"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00900945"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318233b36a"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2014.04.009"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jon199883148"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/17482960903062137"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2011.11.262"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2014.06.052"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2009.186833"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/146608200300079536"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2007.09.143"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(99)00210-5"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1011634"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(82)80286-2"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/21678421.2014.913636"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25034"}],"container-title":["Muscle &amp; 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