{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T03:04:56Z","timestamp":1774148696994,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,5,30]],"date-time":"2017-05-30T00:00:00Z","timestamp":1496102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008792","name":"Novartis Pharma","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008792","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>We analyzed the burden of illness of sporadic inclusion body myositis (sIBM) patients and the costs to the healthcare system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective cohort analysis of 333 sIBM patients aged\u2009\u2265\u200950 years was performed using United States (U.S.) claims data. sIBM patients were matched in a 1:5 ratio to randomly selected individuals with \u22651 healthcare encounter within the year of index date.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>sIBM patients presented with higher rates of disease\u2010 and muscle\u2010related conditions, such as myalgia, myositis, muscle weakness, dysphagia, pneumonia, and falls. Use of healthcare resources, including physical therapy, office visits, emergency room (ER) visits, and hospitalizations, was greater in sIBM patients. This was also reflected in significantly higher overall healthcare costs in the sIBM population driven mainly by more all\u2010cause office visits, all\u2010cause ER visits and hospitalizations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>sIBM imposes a substantial burden on U.S. patients in terms of additional healthcare usage and associated costs. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>56<\/jats:bold>: 861\u2013867, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.25686","type":"journal-article","created":{"date-parts":[[2017,5,11]],"date-time":"2017-05-11T16:08:13Z","timestamp":1494518893000},"page":"861-867","source":"Crossref","is-referenced-by-count":16,"title":["Burden of illness and healthcare resource use in United States patients with sporadic inclusion body myositis"],"prefix":"10.1002","volume":"56","author":[{"given":"Gorana","family":"Capkun","sequence":"first","affiliation":[{"name":"Novartis AG Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aoife","family":"Callan","sequence":"additional","affiliation":[{"name":"Novartis Global Service Center Dublin  Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haijun","family":"Tian","sequence":"additional","affiliation":[{"name":"Novartis Pharmaceuticals Corporation East Hanover New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhongyuan","family":"Wei","sequence":"additional","affiliation":[{"name":"KMK Consulting, Inc. 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