{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T21:23:29Z","timestamp":1760217809022,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,5,23]],"date-time":"2017-05-23T00:00:00Z","timestamp":1495497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study seeks to determine whether the use of Eulerian video magnification (EVM) increases the detection of muscle fasciculations in people with amyotrophic lateral sclerosis (PALS) compared with direct clinical observation (DCO).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010second\u2010long video recordings were taken of 9 body regions of 7 PALS and 7 controls, and fasciculations were counted by DCO during the same 30\u2010s period. The video recordings were then motion magnified and reviewed by 2 independent assessors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In PALS, median fasciculation count per body region was 1 by DCO (range 0\u201310) and 3 in the EVM recordings (range 0\u201315; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.0001). EVM revealed more fasciculations than DCO in 61% of recordings. In controls, median fasciculation count was 0 for both DCO and EVM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Compared with DCO, EVM significantly increased the detection of fasciculations in body regions of PALS. When it is used to supplement clinical examination, EVM has the potential to facilitate the diagnosis of ALS. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>56<\/jats:bold>: 1063\u20131067, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/mus.25690","type":"journal-article","created":{"date-parts":[[2017,5,13]],"date-time":"2017-05-13T08:42:28Z","timestamp":1494664948000},"page":"1063-1067","source":"Crossref","is-referenced-by-count":6,"title":["Using Eulerian video magnification to enhance detection of fasciculations in people with amyotrophic lateral sclerosis"],"prefix":"10.1002","volume":"56","author":[{"given":"Ludo","family":"Van Hillegondsberg","sequence":"first","affiliation":[{"name":"Division of Neurology, Department of Medicine, Faculty of Medicine and Health Sciences Stellenbosch University Tygerberg 7505 South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Carr","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Medicine, Faculty of Medicine and Health Sciences Stellenbosch University Tygerberg 7505 South Africa"},{"name":"Centre for Research in Neurodegenerative Disease, Faculty of Medicine and Health Sciences Stellenbosch University Tygerberg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naeem","family":"Brey","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Medicine, Faculty of Medicine and Health Sciences Stellenbosch University Tygerberg 7505 South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4006-8101","authenticated-orcid":false,"given":"Franclo","family":"Henning","sequence":"additional","affiliation":[{"name":"Division of Neurology, Department of Medicine, Faculty of Medicine and Health Sciences Stellenbosch University Tygerberg 7505 South Africa"},{"name":"Centre for Research in Neurodegenerative Disease, Faculty of Medicine and Health Sciences Stellenbosch University Tygerberg South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60944-1"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/146608200300079536"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2007.09.143"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/21678421.2014.964258"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/17482961003777462"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/21678421.2014.887118"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.5692\/clinicalneurol.54.1083"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.5692\/clinicalneurol.54.1080"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/14660820510027035"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2011.11.262"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2014.06.052"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.5692\/clinicalneurol.53.1206"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880141217"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.10115"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00900945"},{"issue":"4","key":"e_1_2_6_17_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1145\/2185520.2185561","article-title":"Eulerian video magnification for revealing subtle changes in the world","volume":"31","author":"Wu H\u2010Y","year":"2012","journal-title":"ACM Trans Graph"},{"key":"e_1_2_6_18_1","unstructured":"DavisA BoumanKL ChenJG RubinsteinM DurandF BuyukozturkO et al.Visual vibrometry: estimating material properties from small motions in video. 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