{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:13:43Z","timestamp":1792192423516,"version":"4.4.0"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,7,7]],"date-time":"2017-07-07T00:00:00Z","timestamp":1499385600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"MRC","doi-asserted-by":"publisher","award":["G0601943"],"award-info":[{"award-number":["G0601943"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000765","name":"UCL","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000765","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    <jats:italic>Introduction:<\/jats:italic>\n                    Foot deformities are frequent complications in Charcot\u2013Marie\u2013Tooth disease (CMT) patients, often requiring orthopedic surgery. However, there are no prospective, randomized studies on surgical management, and there is variation in the approaches among centers both within and between countries.\n                    <jats:italic>Methods:<\/jats:italic>\n                    In this study we assessed the frequency of foot deformities and surgery among patients recruited into the Inherited Neuropathies Consortium (INC). We also designed a survey addressed to orthopedic surgeons at INC centers to determine whether surgical approaches to orthopedic complications in CMT are variable.\n                    <jats:italic>Results:<\/jats:italic>\n                    Foot deformities were reported in 71% of CMT patients; 30% of the patients had surgery. Survey questions were answered by 16 surgeons working in different specialized centers. Most of the respondents were foot and ankle surgeons. There was marked variation in surgical management.\n                    <jats:italic>Discussion:<\/jats:italic>\n                    Our findings confirm that the approaches to orthopedic management of CMT are varied. We identify areas that require further research.\n                    <jats:italic>Muscle Nerve<\/jats:italic>\n                    <jats:bold>57<\/jats:bold>\n                    : 255\u2013259, 2018\n                  <\/jats:p>","DOI":"10.1002\/mus.25724","type":"journal-article","created":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T14:14:57Z","timestamp":1497968097000},"page":"255-259","source":"Crossref","is-referenced-by-count":75,"title":["Prevalence and orthopedic management of foot and ankle deformities in Charcot\u2013Marie\u2013Tooth disease"],"prefix":"10.1002","volume":"57","author":[{"given":"Matilde","family":"Laur\u00e1","sequence":"first","affiliation":[{"name":"Medical Research Council Centre for Neuromuscular Diseases University College London Institute of Neurology Queen Square London WC1N 3BG UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dishan","family":"Singh","sequence":"additional","affiliation":[{"name":"Foot and ankle unit Royal National Orthopedic Hospital Stanmore UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gita","family":"Ramdharry","sequence":"additional","affiliation":[{"name":"School of Rehabilitation Sciences St George's University of London\/Kingston University London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasper","family":"Morrow","sequence":"additional","affiliation":[{"name":"Medical Research Council Centre for Neuromuscular Diseases University College London Institute of Neurology Queen Square London WC1N 3BG UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariola","family":"Skorupinska","sequence":"additional","affiliation":[{"name":"Medical Research Council Centre for Neuromuscular Diseases University College London Institute of Neurology Queen Square London WC1N 3BG UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Pareyson","sequence":"additional","affiliation":[{"name":"Department of Neurology IRCCS Foundation, Carlo Besta Neurological Institute Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Burns","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences University of Sydney &amp; Children's Hospital at Westmead Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Neurology Cedars Sinai Medical Center West Hollywood California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven S.","family":"Scherer","sequence":"additional","affiliation":[{"name":"Department of Neurology Hospital of the University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David N.","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Rochester Rochester New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Cullen","sequence":"additional","affiliation":[{"name":"Foot and ankle unit Royal National Orthopedic Hospital Stanmore UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Bradish","sequence":"additional","affiliation":[{"name":"Orthopaedic and Spinal Surgery Unit Great Ormond Street Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Gaiani","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics ASL Imola Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicol\u00f2","family":"Martinelli","sequence":"additional","affiliation":[{"name":"Department of Ankle and Foot Surgery IRCCS Galeazzi Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Gibbons","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences University of Sydney &amp; Children's Hospital at Westmead Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn","family":"Pfeffer","sequence":"additional","affiliation":[{"name":"Department of Neurology Cedars Sinai Medical Center West Hollywood California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phinit","family":"Phisitkul","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic and Rehabilitation University of Iowa Health Care Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Wapner","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Sanders","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics University of Rochester Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Flemister","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics University of Rochester Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Shy","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Iowa health Care, Iowa City Iowa USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary M.","family":"Reilly","sequence":"additional","affiliation":[{"name":"Medical Research Council Centre for Neuromuscular Diseases University College London Institute of Neurology Queen Square London WC1N 3BG UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Inherited Neuropathies Consortium","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,7,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2011.00324.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198909000-00038"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/107110079301400809"},{"key":"e_1_2_6_5_1","first-page":"e30","article-title":"et al","volume":"97","author":"Faldini C","year":"2015","journal-title":"Surgical treatment of cavus foot in Charcot\u2010Marie\u2010tooth disease: a review of twenty\u2010four cases: AAOS exhibit selection. J Bone Joint Surg Am"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.G.01356"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fas.2009.10.002"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e32834e9051"},{"key":"e_1_2_6_9_1","first-page":"873","article-title":"et al","volume":"86","author":"Fridman V","year":"2015","journal-title":"CMT subtypes and disease burden in patients enrolled in the Inherited Neuropathies Consortium natural history study: a cross\u2010sectional analysis. J Neurol Neurosurg Psychiatry"},{"key":"e_1_2_6_10_1","first-page":"465","article-title":"et al","volume":"120","author":"Thomas PK","year":"1997","journal-title":"The phenotypic manifestations of chromosome 17p11.2 duplication. Brain"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880170112"},{"key":"e_1_2_6_12_1","first-page":"972","article-title":"et al","volume":"252","author":"Marques W","year":"2005","journal-title":"17p duplicated Charcot\u2013Marie\u2013Tooth 1A. J Neurol"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.23622"}],"container-title":["Muscle &amp; Nerve"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmus.25724","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mus.25724","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T13:48:23Z","timestamp":1695736103000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mus.25724"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,7]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1002\/mus.25724"],"URL":"https:\/\/doi.org\/10.1002\/mus.25724","archive":["Portico"],"relation":{},"ISSN":["0148-639X","1097-4598"],"issn-type":[{"value":"0148-639X","type":"print"},{"value":"1097-4598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,7]]}}}