{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:53:52Z","timestamp":1791928432590,"version":"4.3.4"},"reference-count":70,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T00:00:00Z","timestamp":1511913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["#1K23NS091511\u201001"],"award-info":[{"award-number":["#1K23NS091511\u201001"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Periodic paralyses (PPs) are rare neuromuscular disorders caused by mutations in skeletal muscle sodium, calcium, and potassium channel genes. PPs include hypokalemic paralysis, hyperkalemic paralysis, and Andersen\u2010Tawil syndrome. Common features of PP include autosomal dominant inheritance, onset typically in the first or second decades, episodic attacks of flaccid weakness, which are often triggered by diet or rest after exercise. Diagnosis is based on the characteristic clinic presentation then confirmed by genetic testing. In the absence of an identified genetic mutation, documented low or high potassium levels during attacks or a decrement on long exercise testing support diagnosis. The treatment approach should include both management of acute attacks and prevention of attacks. Treatments include behavioral interventions directed at avoidance of triggers, modification of potassium levels, diuretics, and carbonic anhydrase inhibitors.\n                    <jats:italic>Muscle Nerve<\/jats:italic>\n                    <jats:bold>57<\/jats:bold>\n                    : 522\u2013530, 2018\n                  <\/jats:p>","DOI":"10.1002\/mus.26009","type":"journal-article","created":{"date-parts":[[2017,11,10]],"date-time":"2017-11-10T10:32:37Z","timestamp":1510309957000},"page":"522-530","source":"Crossref","is-referenced-by-count":227,"title":["Review of the Diagnosis and Treatment of Periodic Paralysis"],"prefix":"10.1002","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0790-5315","authenticated-orcid":false,"given":"Jeffrey M.","family":"Statland","sequence":"first","affiliation":[{"name":"Department of Neurology University of Kansas Medical Center 3901 Rainbow Boulevard, Kansas City Kansas 66160 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Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria A.","family":"Sansone","sequence":"additional","affiliation":[{"name":"The NEMO Center, Neurorehabilitation Unit University of Milan  Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Perry B.","family":"Shieh","sequence":"additional","affiliation":[{"name":"Department of Neurology University of California at Los Angeles School of Medicine Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabi N.","family":"Tawil","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Rochester School of Medicine and Dentistry Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaya","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Department of Neurology University of Texas Southwestern Medical Center Dallas Texas 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