{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T09:16:02Z","timestamp":1787908562242,"version":"build-2784847793"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,1,11]],"date-time":"2018-01-11T00:00:00Z","timestamp":1515628800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Finnish Association for the Study of Pain"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Muscle and Nerve"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Introduction<\/jats:italic>: The p.A1156T mutation alters the function of the voltage\u2010gated sodium channel Nav1.4 on the muscle sarcolemma, causing a channelopathy without overt myotonia or periodic paralysis but with myalgic pain. <jats:italic>Methods<\/jats:italic>: A postal survey was conducted to assess the prevalence and characteristics of pain and related symptoms in individuals with the p.A1156T mutation. A specific questionnaire, intensity and interference subscales of the Brief Pain Inventory, pain drawing, Widespread Pain Index, quality of life (RAND\u201036), and the Beck Depression Inventory were completed. <jats:italic>Results<\/jats:italic>: Twenty of 24 patients replied. Current pain was reported by 16 respondents; the other 4 had experienced pain previously. Most commonly, pain was widespread and exercise\u2010induced. The severity and the impact of pain on daily life were considerable, although varied. <jats:italic>Discussion<\/jats:italic>: This sodium channelopathy is another entity in the growing number of diseases causing widespread myalgic pain that resembles the pain seen in fibromyalgia syndrome. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>57<\/jats:bold>: 1014\u20131017, 2018<\/jats:p>","DOI":"10.1002\/mus.26050","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T09:31:17Z","timestamp":1514107877000},"page":"1014-1017","source":"Crossref","is-referenced-by-count":6,"title":["Pain in <i>SCN4A<\/i> Mutated P.A1156T muscle sodium channelopathy\u2014a postal survey"],"prefix":"10.1002","volume":"57","author":[{"given":"Kimmo","family":"Suokas","sequence":"first","affiliation":[{"name":"Department of Neurology Tampere University Hospital P.O. Box 2000 FI\u201033521 Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Palmio","sequence":"additional","affiliation":[{"name":"Neuromuscular Research Center University Hospital of Tampere Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satu","family":"Sandell","sequence":"additional","affiliation":[{"name":"Department of Neurology Southern Ostrobothnia Hospital District Sein\u00e4joki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjarne","family":"Udd","sequence":"additional","affiliation":[{"name":"Neuromuscular Research Center University Hospital of Tampere Tampere Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aki","family":"Hietaharju","sequence":"additional","affiliation":[{"name":"Department of Neurology Tampere University Hospital P.O. 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