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This review uses a series of case studies to discuss the diagnosis and treatment of cancer\u2010related nerve and muscle disorders. Oncologic treatment interventions such as surgery, chemotherapy, radiation therapy, and hormonal therapy, often have predictable side\u2010effects, and sometimes their associated disability can be mitigated, especially if recognized early. Disease progression can mimic other diagnoses. The case studies provide a lens through which to study the presenting symptoms, differential diagnoses, diagnostic evaluation, and treatment interventions. These are all considered within the context of the patient's prognosis and health\u2010related quality of life.<jats:italic>Muscle Nerve<\/jats:italic><jats:bold>58<\/jats:bold>: 335\u2013343, 2018<\/jats:p>","DOI":"10.1002\/mus.26103","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T19:52:29Z","timestamp":1519242749000},"page":"335-343","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Neuromuscular dysfunction in the cancer patient: Evaluation and treatment"],"prefix":"10.1002","volume":"58","author":[{"given":"Jennifer A.","family":"Baima","sequence":"first","affiliation":[{"name":"Department of Orthopedics and Physical Rehabilitation University of Massachusetts Medical School, 119 Belmont Street Worcester Massachusetts 01605 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie K.","family":"Silver","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Harvard Medical School Boston Massachusetts USA"},{"name":"Spaulding Rehabilitation Hospital Charlestown Massachusetts USA"},{"name":"Massachusetts General Hospital Boston Massachusetts USA"},{"name":"Brigham and Women's Hospital Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathew","family":"Most","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Physical Rehabilitation University of Massachusetts Medical School, 119 Belmont Street Worcester Massachusetts 01605 USA"},{"name":"Division of Orthopedic Oncology University of Massachusetts Medical School Worcester Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,25]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Surveillance Epidemiology and End Results [SEER] Program cancer stat facts: cancer of any site. 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