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Data now support the presence of both presynaptic and postsynaptic dysfunction in MuSK\u2010MG. This is 1 of many key differences between MuSK\u2010MG and acetylcholine receptor antibody\u2010MG (AChR\u2010MG), especially as it pertains to potential therapeutic implications. In comparison to AChR\u2010MG, MuSK\u2010MG is generally more refractory to treatment. However, because MuSK\u2010MG is better understood and more readily recognized today, there are more reports of a relatively benign course. The most effective immunotherapies for MuSK\u2010MG are corticosteroids, plasmapheresis, and rituximab. With appropriate therapy, most patients with MuSK\u2010MG achieve minimal manifestation status or better on the postintervention status outlined by the Myasthenia Gravis Foundation of America. A minority of patients remain refractory to treatment, and optimal management for this group remains a considerable challenge.\n                    <jats:italic>Muscle Nerve<\/jats:italic>\n                    <jats:bold>58<\/jats:bold>\n                    : 344\u2013358, 2018\n                  <\/jats:p>","DOI":"10.1002\/mus.26107","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T14:52:19Z","timestamp":1519224739000},"page":"344-358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Myasthenia gravis with muscle\u2010specific tyrosine kinase antibodies: A narrative review"],"prefix":"10.1002","volume":"58","author":[{"given":"John","family":"Morren","sequence":"first","affiliation":[{"name":"Neuromuscular Center, Neurological Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk S90 Cleveland Ohio 44195 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