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In contrast, the late effects of poliomyelitis are often a consequence of biomechanical alterations that occur as a result of polio\u2010related surgeries, musculoskeletal deformities, or weakness. Osteoporosis and fractures of the polio\u2010involved limbs are common. A comprehensive clinical evaluation with appropriate investigations is essential to fulfilling the established PPS diagnostic criteria. PPS is a diagnosis of exclusion in which a key clinical feature required for the diagnosis is new muscle weakness and\/or muscle fatigability that is persistent for at least 1 year. Electromyographic and muscle biopsy findings including evidence of ongoing denervation cannot reliably distinguish between patients with or without PPS. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>58<\/jats:bold>:751\u2013759, 2018<\/jats:p>","DOI":"10.1002\/mus.26168","type":"journal-article","created":{"date-parts":[[2018,5,12]],"date-time":"2018-05-12T09:31:48Z","timestamp":1526117508000},"page":"751-759","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Postpolio syndrome and the late effects of poliomyelitis. 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