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The protocol included structural T1\u2010weighted images, DIXON sequences for fat fraction calculation, T2 values quantification and diffusion MRI. Region of interest analysis was performed on 4 different compartments (anterior compartment, posterior compartment, gracilis, sartorius). <jats:italic>Results<\/jats:italic>: Patients showed high levels of fat infiltration as measured by DIXON sequences. Sartorius and anterior compartment were more infiltrated in LGMD2B than LGMD2A patients. T2 values were mildly reduced in both disorders. Correlations between clinical scores and qMRI were found. <jats:italic>Conclusions<\/jats:italic>: qMRI measures may help to quantify muscular degeneration, but careful interpretation is needed when fat infiltration is massive. <jats:italic>Muscle Nerve<\/jats:italic> <jats:bold>58<\/jats:bold>: 550\u2013558, 2018<\/jats:p>","DOI":"10.1002\/mus.26189","type":"journal-article","created":{"date-parts":[[2018,7,20]],"date-time":"2018-07-20T14:50:12Z","timestamp":1532098212000},"page":"550-558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Multiparametric quantitative MRI assessment of thigh muscles in limb\u2010girdle muscular dystrophy 2A and 2B"],"prefix":"10.1002","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5508-1149","authenticated-orcid":false,"given":"Filippo","family":"Arrigoni","sequence":"first","affiliation":[{"name":"Neuroimaging Lab, Scientific Institute, IRCCS E. Medea  Via don L. 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